Evidence map›Paper›PMID 37094980›Full record

Observational studyRMD open2023

Performance of the 2022 ACR/EULAR giant cell arteritis classification criteria for diagnosis in patients with suspected giant cell arteritis in routine clinical care.

Juan Molina-Collada, Isabel Castrejón, Irene Monjo, Elisa Fernández-Fernández, Gabriela Torres Ortiz, Jose María Álvaro-Gracia, Eugenio de Miguel

Abstract readObservational Study
In one paragraph

Observational study in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  10. Diagnosing vasculitis with ultrasound: findings and pitfalls.Therapeutic advances in musculoskeletal disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan Molina-ColladaDepartment of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain molinacolladajuan@gmail.com.ORCID 0000-0001-5191-7802
Isabel CastrejónDepartment of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Irene MonjoDepartment of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-3252-8016
Elisa Fernández-FernándezDepartment of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-1628-5042
Gabriela Torres OrtizDepartment of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.
Jose María Álvaro-GraciaDepartment of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Eugenio de MiguelDepartment of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0001-5146-1964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the performance of the new 2022 American College of Rheumatology (ACR)/EULAR giant cell arteritis (GCA) classification criteria for diagnosis in routine clinical care.

methodsMulticentric retrospective observational study of patients referred to two ultrasound (US) fast track clinics. Patients with GCA were compared with unselected controls with suspected GCA. The gold standard for GCA diagnosis has been clinical confirmation after 6 months of follow-up. All patients underwent an US exam of temporal and extracranial arteries (carotid, subclavian and axillary) at baseline. Fluorodeoxyglucose-positron emission tomography/CT was performed according to standard clinician criteria. The performance of the new 2022 ACR/EULAR GCA classification criteria was evaluated in all patients with GCA across different subsets of the disease.

resultsA total of 319 patients (188 cases, 131 controls) were included for analysis (mean age 76 years, 58.9% females). Overall, the 2022 EULAR/ACR GCA classification criteria had a sensitivity of 92.6% and a specificity of 71.8%, using GCA clinical diagnosis as external criterion and the area under the curve (AUC) was 0.928 (95% CI 0.899 to 0.957). Isolated large vessel-GCA showed a sensitivity of 62.2% and a specificity of 71.8% (AUC 0.691 (0.592 to 0.790)), while biopsy-proven GCA showed a sensitivity of 100% and a specificity of 71.8% (AUC 0.989 (0.976 to 1)). Overall sensitivity and specificity of the 1990 ACR criteria was 53.2% and 80.2%, respectively.

conclusionsThe new 2022 ACR/EULAR GCA classification criteria showed adequate diagnostic accuracy in patients with suspected GCA under routine care, and an improvement on the sensitivity and specificity of the 1990 ACR classification criteria in all patient subsets.

Indexed as

Giant Cell ArteritisRheumatologyAgedCarotid ArteriesFemaleHumansMaleSensitivity and SpecificityTemporal ArteriesUnited Statesgiant cell arteritissystemic vasculitisultrasonography

Identifiers

PMID37094980
PMCPMC10151996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.