Evidence map›Paper›PMID 37094746›Full record

ArticlePhysiology & behavior2023

Relation of BOLD response to food-specific and generic motor response inhibition tasks to body fat gain in adults with overweight and obesity.

Sonja Yokum, Eric Stice

Open access · greenAbstract read
In one paragraph

Article in Physiology & behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sonja YokumOregon Research Institute, 3800 Sports Way, Springfield OR 97477, USA. Electronic address: sonjas@ori.org.
Eric SticeDepartment of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford CA 94305, USA.
Oregon Research Institute · USStanford University · US

Funding

Translational Neuroscience: Response Training for Obesity Treatment.R01DK112762 · NIDDK · STANFORD UNIVERSITY · PI STICE, ERIC M · 2017 to 2021
$2.4M
NIDDK NIH HHS R01 DK112762
6 · The paper itself

Abstract

backgroundLow inhibitory control has been theorized to contribute to the development and maintenance of obesity. Knowledge on the neurobiological indicators of inhibitory control deficits predicting future weight gain is limited. The current study examined if individual differences in blood-oxygenation-level-dependent (BOLD) activity associated with food-specific and general motor response inhibition predict future body fat change in adults with overweight or obesity.

methodsBOLD activity and behavioral responses of adults with overweight or obesity (N = 160) were recorded while performing a food-specific stop signal task (n = 92) or a generic stop signal task (n = 68). Percent body fat was measured at baseline, posttest, 3-month, and 6-month follow-up.

resultsElevated BOLD activity in somatosensory (postcentral gyrus), and attention (precuneus) regions during successful inhibition in the food-specific stop signal task and elevated BOLD activity in a motor region (anterior cerebellar lobe) in the generic stop signal task predicted greater body fat gain over 6-month follow-up. Elevated BOLD activity in inhibitory control regions (inferior-, middle-, superior frontal gyri) and error monitoring regions (anterior cingulate cortex, insula) during erroneous responses in the generic stop signal task predicted body fat loss.

conclusionsResults suggest that improving motor response inhibition and error monitoring may facilitate weight loss in adults with overweight and obesity.

Indexed as

BrainOverweightAdipose TissueAdultBrain MappingHumansMagnetic Resonance ImagingObesityBody fat gainError monitoringInhibitory controlObesityStop signal

Identifiers

PMID37094746
PMCPMC10205669
OpenAlexW4366753640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.