Evidence map›Paper›PMID 37094486›Full record

ReviewCurrent opinion in genetics & development2023

Exploring the heterogeneity of white adipose tissue in mouse and man.

Margo P Emont, Evan D Rosen

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Adipose 'neighborhoods' collaborate to maintain metabolic health.Current opinion in genetics & development · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Margo P EmontDivision of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, USA; Harvard Medical School, USA; Broad Institute, USA.
Evan D RosenDivision of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, USA; Harvard Medical School, USA; Broad Institute, USA. Electronic address: erosen@bidmc.harvard.edu.

Funding

Investigating Human Adipocyte HeterogeneityRC2DK116691 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Orr Ashenberg, Noel P Burtt · 2018 to 2026
$17.8M
Investigating the regulation of distinct human adipocyte subpopulationsK01DK134806 · NIDDK · UNIVERSITY OF CHICAGO · PI Margo Preminger Emont · 2023 to 2026
$592k
NIDDK NIH HHS K01 DK134806NIDDK NIH HHS RC2 DK116691
6 · The paper itself

Abstract

Adipose tissue is a heterogeneous organ, comprising cell types, including mature adipocytes, progenitor cells, immune cells, and vascular cells. Here, we discuss the heterogeneity of human and mouse white adipose tissue in general and white adipocytes specifically, focusing on how our understanding of adipocyte subpopulations has expanded with the advent of single nuclear RNA sequencing and spatial transcriptomics. Furthermore, we discuss critical remaining questions regarding how these distinct populations arise, how their functions differ from one another, and which potentially contribute to metabolic pathophysiology.

Indexed as

Adipose TissueAdipose Tissue, WhiteAdipocytes, WhiteHumansStem Cells

Identifiers

PMID37094486
PMCPMC10330284

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.