Evidence map›Paper›PMID 37094132›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via

Juanye Zhang, Yingying Ning, Hua Zhu, Nicholas J Rotile, He Wei, Himashinie Diyabalanage, Eric C Hansen, Iris Y Zhou, Stephen C Barrett, Mozhdeh Sojoodi and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  8. Quantitative in Vivo Molecular MRI.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Juanye ZhangDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-1827-3395
Yingying NingAthinoula A. Martinos Center for Biomedical Imaging, Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129.
Hua ZhuDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Nicholas J RotileAthinoula A. Martinos Center for Biomedical Imaging, Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129.
He WeiDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Himashinie DiyabalanageCollagen Medical, Boston, MA 02478.
Eric C HansenDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Iris Y ZhouAthinoula A. Martinos Center for Biomedical Imaging, Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129.ORCID 0000-0002-4351-7398
Stephen C BarrettDivision of Gastrointestinal and Oncological Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.
Mozhdeh SojoodiDivision of Gastrointestinal and Oncological Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.ORCID 0000-0002-9946-5910
Kenneth K TanabeDivision of Gastrointestinal and Oncological Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.
Valerie HumbletCollagen Medical, Boston, MA 02478.
Alan JasanoffDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-2834-6359
Peter CaravanAthinoula A. Martinos Center for Biomedical Imaging, Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129.ORCID 0000-0002-3179-6537
Moungi G BawendiDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Massachusetts Institute of Technology · USMassachusetts General Hospital · USHarvard University · USCollagen Medical (United States) · US

Funding

Wide-Field Short-Wave Infrared (SWIR) multiphoton (MP) tissue imagingP41EB015871 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SO, PETER T. · 2012 to 2021
$11.3M
Molecular MR Imaging of Hepatic FibrogenesisR01DK121789 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Peter D Caravan · 2019 to 2026
$5.0M
Carbon-13 Polarizer for Metabolic MR ImagingS10OD021768 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI YEN, YI-FEN · 2017 to 2017
$1.9M
Quantitative MRI-PET Imaging of Pulmonary FibrosisK25HL148837 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ZHOU, IRIS YUWEN · 2020 to 2023
$686k
Inductively Coupled Plasma Mass SpectrometerS10OD032138 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2022 to 2022
$598k
Electronics Upgrade for 11.7 TS10OD025234 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2018 to 2018
$595k
HPLC-ICP-MS SystemS10OD010650 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2013 to 2013
$371k
New class of collagen-targeted contrast agents for Magnetic Resonance ImagingR43EB030959 · NIBIB · COLLAGEN MEDICAL, LLC · PI HUMBLET, VALERIE · 2021 to 2021
$287k
NHLBI NIH HHS K25 HL148837NIBIB NIH HHS P41 EB015871NIBIB NIH HHS R43 EB030959NIDDK NIH HHS R01 DK121789NIH HHS S10 OD010650NIH HHS S10 OD021768NIH HHS S10 OD025234NIH HHS S10 OD032138
6 · The paper itself

Abstract

SNIO-CBP, a single-nanometer iron oxide (SNIO) nanoparticle functionalized with a type I collagen-binding peptide (CBP), was developed as a

Indexed as

Magnetite NanoparticlesNanoparticlesAnimalsCollagenContrast MediaDisease Models, AnimalFerric CompoundsLiverLiver CirrhosisMagnetic Iron Oxide NanoparticlesMagnetic Resonance ImagingMiceCollagenContrast MediaFerric Compoundsferric oxideMagnetite Nanoparticlescontrast agentiron oxide nanoparticlesliver fibrosisMRItargeted delivery

Identifiers

PMID37094132
PMCPMC10161015
OpenAlexW4366816348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.