Evidence map›Paper›PMID 37094126›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage.

Manling Zhang, Ruchao Peng, Qi Peng, Sheng Liu, Zhiteng Li, Yuqin Zhang, Hao Song, Jia Yang, Xiao Xing, Peiyi Wang and 2 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Manling ZhangChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Ruchao PengChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-2741-6212
Qi PengChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Sheng LiuCryo-EM Centre, Department of Biology, Southern University of Science and Technology, Shenzhen 518055, China.
Zhiteng LiSavaid Medical School, University of Chinese Academy of Sciences, Beijing 100049, China.
Yuqin ZhangChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Hao SongResearch Network of Immunity and Health, Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-2811-0370
Jia YangShanxi Academy of Advanced Research and Innovation, 030032 Taiyuan, Shanxi, China.
Xiao XingShanxi Academy of Advanced Research and Innovation, 030032 Taiyuan, Shanxi, China.
Peiyi WangCryo-EM Centre, Department of Biology, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0001-7737-181X
Jianxun QiChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-9358-4732
George F GaoChinese Academy of Sciences (CAS), Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-3869-615X
Chinese Academy of Sciences · CNShanxi Academy of Building Research · CNSouthern University of Science and Technology · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRISPR-Cas systems are widespread adaptive antiviral systems used in prokaryotes. Some phages, in turn, although have small genomes can economize the use of genetic space to encode compact or incomplete CRISPR-Cas systems to inhibit the host and establish infection. Phage ICP1, infecting

Indexed as

BacteriophagesCRISPR-Associated ProteinsCRISPR-Cas SystemsDNACRISPR-Associated ProteinsDNAcompactCRISPR-Cas systeminterferencephage

Identifiers

PMID37094126
PMCPMC10161043
OpenAlexW4366816423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.