Evidence map›Paper›PMID 37093984›Full record

ArticleMagnetic resonance in medicine2023

Evaluation of contributors to amide proton transfer-weighted imaging and nuclear Overhauser enhancement-weighted imaging contrast in tumors at a high magnetic field.

Jing Cui, Yu Zhao, Casey Sun, Junzhong Xu, Zhongliang Zu

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  10. Prediction of Kirsten rat sarcoma (Quantitative imaging in medicine and surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing CuiVanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA.ORCID 0000-0003-0902-8715
Yu ZhaoVanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA.ORCID 0000-0002-2814-591X
Casey SunVanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA.ORCID 0000-0002-7542-4540
Junzhong XuVanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA.ORCID 0000-0001-7895-4232
Zhongliang ZuVanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA.ORCID 0000-0001-7361-7480

Funding

Nuclear Overhauser enhancement (NOE) MR imaging of choline phospholipids and their metabolismR01EB029443 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZU, ZHONGLIANG · 2021 to 2024
$1.5M
Validation of CEST MR Imaging of Creatine and Phosphocreatine in MuscleR21AR074261 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZU, ZHONGLIANG · 2018 to 2019
$382k
Optimizing Glutamate Imaging using CEST MRI at 3T Clinical ScannersR03EB029078 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZU, ZHONGLIANG · 2020 to 2021
$170k
NIAMS NIH HHS R21 AR074261NIBIB NIH HHS R01 EB029443NIBIB NIH HHS R03 EB029078NIH HHS R01 EB029443NIH HHS R03 EB029078NIH HHS R21 AR074261
6 · The paper itself

Abstract

purposeThe purpose is to evaluate the relative contribution from confounding factors (T

methodsWe first provided a signal model that shows the separate dependence of CESTR on these confounding factors and the clean CEST/NOE effects quantified by an apparent exchange-dependent relaxation (AREX) method. We then measured the change in these effects in the 9-L tumor model in rats, through which we calculated the relative contribution of each confounding factor. f

resultsThe CESTR-quantified APT shows "positive" contrast in tumors, which arises primarily from R

conclusionCESTR reflects a combined effect of T

Indexed as

Brain NeoplasmsAmidesAnimalsImage EnhancementMagnetic Resonance ImagingProtonsRatsAmidesProtonschemical exchange saturation transfer (CEST)magnetization transfer (MT)nuclear Overhauser enhancement (NOE)tumor

Identifiers

PMID37093984
PMCPMC10616782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.