Evidence map›Paper›PMID 37093775›Full record

ArticleMagnetic resonance in medicine2023

Latent signal models: Learning compact representations of signal evolution for improved time-resolved, multi-contrast MRI.

Yamin Arefeen, Junshen Xu, Molin Zhang, Zijing Dong, Fuyixue Wang, Jacob White, Berkin Bilgic, Elfar Adalsteinsson

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yamin ArefeenDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0003-2194-1945
Junshen XuDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Molin ZhangDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0003-3852-3184
Zijing DongAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA.ORCID 0000-0001-9334-0968
Fuyixue WangAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA.ORCID 0000-0001-8975-2775
Jacob WhiteDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Berkin BilgicAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA.ORCID 0000-0002-9080-7865
Elfar AdalsteinssonDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

Funding

CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2M
MRI CORTICOGRAPHY: DEVELOPING NEXT GENERATION MICROSCALE HUMAN CORTEX MRI SCANNERU01EB025162 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEINBERG, DAVID ALAN, LIU, CHUNLEI · 2017 to 2021
$13.4M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9M
Advanced Fetal ImagingR01EB017337 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2014 to 2018
$6.2M
Noninvasive Realtime Assessment of Placental Structure and Function with Novel MR Imaging MethodsU01HD087211 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI GRANT, PATRICIA ELLEN, WALD, LAWRENCE L · 2015 to 2015
$4.9M
Neuroimaging Training ProgramT32EB001680 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BRUCE R ROSEN · 2003 to 2026
$3.8M
Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
MRI technology for restoring brain image quality for pediatric patients with metallic orthodontic hardwareR01EB028797 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Berkin Bilgic, Jason P Stockmann · 2020 to 2026
$3.0M
Rapid Fetal HASTE MR ImagingR03EB031175 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BILGIC, BERKIN · 2021 to 2022
$188k
NIBIB NIH HHS P41 EB030006NIBIB NIH HHS R01 EB017337NIBIB NIH HHS R01 EB028797NIBIB NIH HHS R03 EB031175NIBIB NIH HHS T32 EB001680NIBIB NIH HHS U01 EB025162NIBIB NIH HHS U01 EB026996NICHD NIH HHS R01 HD100009NICHD NIH HHS U01 HD087211NIH HHS 5T32EB1680
6 · The paper itself

Abstract

purposeTo improve time-resolved reconstructions by training auto-encoders to learn compact representations of Bloch-simulated signal evolution and inserting the decoder into the forward model.

methodsBuilding on model-based nonlinear and linear subspace techniques, we train auto-encoders on dictionaries of simulated signal evolution to learn compact, nonlinear, latent representations. The proposed latent signal model framework inserts the decoder portion of the auto-encoder into the forward model and directly reconstructs the latent representation. Latent signal models essentially serve as a proxy for fast and feasible differentiation through the Bloch equations used to simulate signal. This work performs experiments in the context of T

resultsAn auto-encoder with 1 real latent variable represents single-tissue fast spin echo, EPTI, and MPRAGE signal evolution to within 0.15% normalized RMS error, enabling reconstruction problems with 3 degrees of freedom per voxel (real latent variable + complex scaling) in comparison to linear models with 4-8 degrees of freedom per voxel. In simulated/in vivo T

conclusionDirectly solving for nonlinear latent representations of signal evolution improves time-resolved MRI reconstructions.

Indexed as

AlgorithmsMagnetic Resonance ImagingComputer SimulationImage Processing, Computer-Assistedimage reconstructionmachine learningmodel-basedtime-resolved MRI

Identifiers

PMID37093775
PMCPMC12554331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.