Evidence map›Paper›PMID 37093495›Full record

ArticleUpdates in surgery2023

Outcomes of surgical treatment of diverticular abscesses after failure of antibiotic therapy.

Alberto Arezzo, Antonella Nicotera, Luca Domenico Bonomo, Francesco Olandese, Simona Veglia, Alice Ferguglia, Giuseppe Pentassuglia, Giuseppe Mingrone, Mario Morino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Updates in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alberto ArezzoDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy. alberto.arezzo@unito.it.ORCID http://orcid.org/0000-0002-2110-4082
Antonella NicoteraDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Luca Domenico BonomoDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Francesco OlandeseDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Simona VegliaDepartment of Diagnostic Imaging and Radiotherapy, AOU Città della Salute e della Scienza di Torino-University of Turin, Turin, Italy.
Alice FergugliaDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Giuseppe PentassugliaDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Giuseppe MingroneDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.
Mario MorinoDepartment of Surgical Sciences, University of Turin, Corso Dogliotti 14, 10126, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of diverticular abscess (DA) is still controversial. Antibiotic therapy is indicated in abscesses ≤ 4 cm, while percutaneous drainage/surgery in abscesses > 4 cm. The study aims to assess the role of antibiotics and surgical treatments in patients affected by DA. We retrospectively analyzed 100 consecutive patients with DA between 2013 and 2020, with a minimum follow-up of 12 months. They were divided into two groups depending on abscess size ≤ or > 4 cm (group 1 and group 2, respectively). All patients were initially treated with intravenous antibiotics. Surgery was considered in patients with generalized peritonitis at admission or after the failure of antibiotic therapy. The primary endpoint was to compare recurrence rates for antibiotics and surgery. The secondary endpoint was to assess the failure rate of each antibiotic regimen resulting in surgery. In group 1, 31 (72.1%) patients were conservatively treated and 12 (27.9%) underwent surgery. In group 2, percentages were respectively 50.9% (29 patients) and 49.1% (28 patients). We observed 4 recurrences in group 1 and 6 in group 2. Recurrence required surgery in 3 patients/group. We administered amoxicillin-clavulanic acid to 74 patients, piperacillin-tazobactam to 14 patients and ciprofloxacin + metronidazole to 12 patients. All patients referred to surgery had been previously treated with amoxicillin-Powered by Editorial Manager

Indexed as

Abdominal AbscessDiverticulitis, ColonicDiverticulosis, ColonicAbscessAmoxicillin-Potassium Clavulanate CombinationAnti-Bacterial AgentsCiprofloxacinColectomyDrainageHumansMetronidazolePiperacillin, Tazobactam Drug CombinationRetrospective StudiesAmoxicillin-Potassium Clavulanate CombinationAnti-Bacterial AgentsCiprofloxacinMetronidazolePiperacillin, Tazobactam Drug CombinationAcute diverticulitisAntibiotic therapyDiverticular abscessEmergency surgeryObservational studyPercutaneous drainage

Identifiers

PMID37093495
PMCPMC10284947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.