Evidence map›Paper›PMID 37093443›Full record

ArticleJournal of assisted reproduction and genetics2023

Clinical and laboratory key performance indicators in IVF: A consensus between the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) and the Italian Society of Embryology, Reproduction and Research (SIERR).

Alberto Vaiarelli, Carlotta Zacà, Valentina Spadoni, Danilo Cimadomo, Alessandro Conforti, Carlo Alviggi, Roberto Palermo, Carlo Bulletti, Lucia De Santis, Valerio Pisaturo and 4 more

Abstract readConsensus Statement
In one paragraph

Article in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  12. The burnout: a silent saboteur in in vitro fertilization laboratories.Journal of assisted reproduction and genetics · 2025
    Review
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alberto Vaiarelli *GeneraLife IVF, Clinica Valle Giulia, Via G. De Notaris, 2B, Rome, Italy. alberto.vaiarelli@gmail.com.ORCID http://orcid.org/0000-0002-0873-3925
Carlotta Zacà *9.Baby, GeneraLife IVF, Bologna, Italy.ORCID http://orcid.org/0000-0002-9017-6805
Valentina Spadoni9.Baby, GeneraLife IVF, Bologna, Italy.
Danilo CimadomoGeneraLife IVF, Clinica Valle Giulia, Via G. De Notaris, 2B, Rome, Italy.ORCID http://orcid.org/0000-0002-5390-9221
Alessandro ConfortiDepartment of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, Naples, Italy.
Carlo AlviggiDepartment of Public Health, Federico II University, Naples, Italy.
Roberto PalermoUnità Di Procreazione Medicalmente Assistita, Centro A.M.B.R.A., Palermo, Italy.
Carlo BullettiDepartment of Obstetrics, Gynecology and Reproductive Science, Yale University, New Haven, CT, USA.
Lucia De SantisObstetrics and Gynaecology Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Valerio PisaturoFondazione IRCCS, Ca' Granda, Ospedale Maggiore, Policlinico Di Milano, Milan, Italy.
Vincenzo VigilianoART Italian National Register, National Center for Diseases Prevention and Health Promotion, National Health Institute, Rome, Italy.
Giulia ScaravelliART Italian National Register, National Center for Diseases Prevention and Health Promotion, National Health Institute, Rome, Italy.
Filippo Maria UbaldiGeneraLife IVF, Clinica Valle Giulia, Via G. De Notaris, 2B, Rome, Italy.
Andrea Borini9.Baby, GeneraLife IVF, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInfertility is increasing worldwide, and many couples seek IVF. Clinical management and laboratory work are fundamental in the IVF journey. Therefore, the definition of reliable key performance indicators (KPIs) based on clinical and laboratory parameters, is essential for internal quality control (IQC). Laboratory performance indicators have been identified and a first attempt to also determine clinical ones has been recently published. However, more detailed indicators are required.

methodsAn Italian group of experts in Reproductive Medicine from both public and private clinics on behalf of SIFES-MR and SIERR was established to define IVF indicators to monitor clinical performance.

resultsThe working group built a consensus on a list of KPIs, performance indicators (PIs) and recommendation indicators (RIs). When deemed necessary, the reference population was stratified by woman age, response to ovarian stimulation and adoption of preimplantation genetic testing for aneuploidies (PGT-A). Each indicator was scored with a value from 1 to 5 and a weighted average formula - considering all the suggested parameters-was defined. This formula generates a center performance score, indicating low, average, good, or excellent performance.

conclusionThis study is intended to provide KPIs, PIs and RIs that encompass several essential aspects of a modern IVF clinic, including quality control and constant monitoring of clinical and embryological features. These indicators could be used to assess the quality of each center with the aim of improving efficacy and efficiency in IVF.

Indexed as

InfertilityReproductive MedicineFemaleFertilityFertilization in VitroHumansItalyReproductionAssisted reproductive technologyConsensus meetingKey performance indicatorsPerformance indicatorsQuality improvementRecommendations

Identifiers

PMID37093443
PMCPMC10310668

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.