Evidence map›Paper›PMID 37093321›Full record

ArticleInsights into imaging2023

Machine learning combined with radiomics and deep learning features extracted from CT images: a novel AI model to distinguish benign from malignant ovarian tumors.

Ya-Ting Jan, Pei-Shan Tsai, Wen-Hui Huang, Ling-Ying Chou, Shih-Chieh Huang, Jing-Zhe Wang, Pei-Hsuan Lu, Dao-Chen Lin, Chun-Sheng Yen, Ju-Ping Teng and 3 more

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Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Ya-Ting JanDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Pei-Shan TsaiDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Wen-Hui HuangDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Ling-Ying ChouDepartment of Radiology, MacKay Memorial Hospital, Taipei, Taiwan.
Shih-Chieh HuangDepartment of Radiology, MacKay Memorial Hospital, Taipei, Taiwan.
Jing-Zhe WangDepartment of Radiology, MacKay Memorial Hospital, Taipei, Taiwan.
Pei-Hsuan LuDepartment of Radiology, MacKay Memorial Hospital, Taipei, Taiwan.
Dao-Chen LinDivision of Endocrine and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chun-Sheng YenDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Ju-Ping TengDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Greta S P MokBiomedical Imaging Laboratory (BIG), Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau, China.
Cheng-Ting Shih *Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, 404, Taiwan. ctshih21@gmail.com.
Tung-Hsin Wu *Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan. tung@ym.edu.tw.ORCID http://orcid.org/0000-0002-0583-7921

Funding

China Medical University CMU111-MF-62National Science and Technology Council MOST 111-2314-B-039-042
6 · The paper itself

Abstract

backgroundTo develop an artificial intelligence (AI) model with radiomics and deep learning (DL) features extracted from CT images to distinguish benign from malignant ovarian tumors.

methodsWe enrolled 149 patients with pathologically confirmed ovarian tumors. A total of 185 tumors were included and divided into training and testing sets in a 7:3 ratio. All tumors were manually segmented from preoperative contrast-enhanced CT images. CT image features were extracted using radiomics and DL. Five models with different combinations of feature sets were built. Benign and malignant tumors were classified using machine learning (ML) classifiers. The model performance was compared with five radiologists on the testing set.

resultsAmong the five models, the best performing model is the ensemble model with a combination of radiomics, DL, and clinical feature sets. The model achieved an accuracy of 82%, specificity of 89% and sensitivity of 68%. Compared with junior radiologists averaged results, the model had a higher accuracy (82% vs 66%) and specificity (89% vs 65%) with comparable sensitivity (68% vs 67%). With the assistance of the model, the junior radiologists achieved a higher average accuracy (81% vs 66%), specificity (80% vs 65%), and sensitivity (82% vs 67%), approaching to the performance of senior radiologists.

conclusionsWe developed a CT-based AI model that can differentiate benign and malignant ovarian tumors with high accuracy and specificity. This model significantly improved the performance of less-experienced radiologists in ovarian tumor assessment, and may potentially guide gynecologists to provide better therapeutic strategies for these patients.

Indexed as

Computed tomographyDeep learningMachine learningOvarian tumorRadiomics

Identifiers

PMID37093321
PMCPMC10126170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.