SynthesisBrain structure & function2023
Accurate localization and coactivation profiles of the frontal eye field and inferior frontal junction: an ALE and MACM fMRI meta-analysis.
Synthesis in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neurodevelopmental commonalities in cognitive control networks for mathematics and reading in meta-analysis of 3308 participants.Nature communications · 2025Pooled it
- Domain-Specific and Domain-General Functional Brain Alterations in Type 2 Diabetes Mellitus: A Task-Based and Functional Connectivity Meta-Analysis.Brain and behavior · 2025Pooled it
- Cognitive-motor dual-task training on gait and balance in stroke patients: meta-analytic report and trial sequential analysis of randomized clinical trials.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Tetrix: A novel Tetris-based paradigm for neuroimaging research and clinical applications.Behavior research methods · 2026Article
- Selectivity for high-level language processing is highly localized in individual brains.bioRxiv : the preprint server for biology · 2026Article
- Aberrant multivariate mapping between behavioral profiles and cortical morphological brain networks in children with autism spectrum disorder.Translational psychiatry · 2026Article
- Visual field inhomogeneities and the architectonics of early visual cortex shape visual working memory.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Functional and Metabolic Abnormalities in Primary Visual Cortex and Frontal Eye Fields and Candidate Biomarkers of Acute Acquired Comitant Esotropia.Investigative ophthalmology & visual science · 2026Article
- Distinct Resting-State Connectomes for Face and Scene Perception Predict Individual Task Performance.Human brain mapping · 2026Article
- Visual awareness of stimulus features shapes motor control through action end-state comfort.Scientific reports · 2026Article
- Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information.eLife · 2025Article
- Frontal Eye Field in the Precentral Sulcus: A Direct Electrical Cortical Stimulation Study With Stereo-EEG Electrodes.Brain and behavior · 2025Article
- The Inferior Frontal Junction Jointly Encodes Target Identity and Feature Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Causal phase-dependent control of non-spatial attention in human prefrontal cortex.Nature human behaviour · 2024Article
- Efferent compared to afferent neural substrates of the vergence eye movement system evoked via fMRI.Frontiers in neuroscience · 2024Article
- Prefrontal Cortex Codes Representations of Target Identity and Feature Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Prefrontal tDCS is unable to modulate mind wandering propensity or underlying functional or effective brain connectivity.Scientific reports · 2022Article
Corrections and comments
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The frontal eye field (FEF) and the inferior frontal junction (IFJ) are prefrontal structures involved in mediating multiple aspects of goal-driven behavior. Despite being recognized as prominent nodes of the networks underlying spatial attention and oculomotor control, and working memory and cognitive control, respectively, the limited quantitative evidence on their precise localization has considerably impeded the detailed understanding of their structure and connectivity. In this study, we performed an activation likelihood estimation (ALE) fMRI meta-analysis by selecting studies that employed standard paradigms to accurately infer the localization of these regions in stereotaxic space. For the FEF, we found the highest spatial convergence of activations for prosaccade and antisaccade paradigms at the junction of the precentral sulcus and superior frontal sulcus. For the IFJ, we found consistent activations across oddball/attention, working memory, task-switching and Stroop paradigms at the junction of the inferior precentral sulcus and inferior frontal sulcus. We related these clusters to previous meta-analyses, sulcal/gyral neuroanatomy, and a comprehensive brain parcellation, highlighting important differences compared to their results and taxonomy. Finally, we leveraged the ALE peak coordinates as seeds to perform a meta-analytic connectivity modeling (MACM) analysis, which revealed systematic coactivation patterns spanning the frontal, parietal, and temporal cortices. We decoded the behavioral domains associated with these coactivations, suggesting that these may allow FEF and IFJ to support their specialized roles in flexible behavior. Our study provides the meta-analytic groundwork for investigating the relationship between functional specialization and connectivity of two crucial control structures of the prefrontal cortex.
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