Evidence map›Paper›PMID 37093107›Full record

SynthesisEpigenetics2023

A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation.

Giulietta S Monasso, Thanh T Hoang, Giulia Mancano, Sílvia Fernández-Barrés, John Dou, Vincent W V Jaddoe, Christian M Page, Laura Johnson, Mariona Bustamante, Kelly M Bakulski and 15 more

Open access · diamondAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Epigenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 6 countries.

Giulietta S MonassoThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Thanh T HoangEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC, USA.
Giulia MancanoMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Sílvia Fernández-BarrésISGlobal, Bacelona Institute for Global Health, Barcelona, Spain.
John DouDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA.
Vincent W V JaddoeThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Christian M PageCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Laura JohnsonMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Mariona BustamanteISGlobal, Bacelona Institute for Global Health, Barcelona, Spain.
Kelly M BakulskiDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA.
Siri E HåbergCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Per M UelandBEVITAL, Bergen, Norway.
Thomas BattramMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Simon K MeridInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Erik MelénInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Doretta CaramaschiCollege of Life and Environmental Sciences, Department of Psychology, University of Exeter, Exeter, UK.
Leanne K KüpersThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Jordi SunyerISGlobal, Bacelona Institute for Global Health, Barcelona, Spain.
Wenche NystadDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.
Sandra G HeilDepartment of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Rebecca J SchmidtDepartment of Public Health Sciences, School of Medicine, University of California Davis, Davis, USA.
Martine VrijheidISGlobal, Bacelona Institute for Global Health, Barcelona, Spain.
Gemma C SharpMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Stephanie J LondonEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC, USA.
Janine F FelixThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0002-9801-5774
Erasmus MC · NLUniversitat Pompeu Fabra · ESUniversity of Bristol · GBNorwegian Institute of Public Health · NOKarolinska Institutet · SENational Institutes of Health · USUniversity of Michigan · USBevital (Norway) · NOUniversity of California, Davis · USUniversity of Exeter · GB

Funding

Genetic And Environmental Factors In Childhood Respiratory HealthZIAES049019 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.8M
BUILDS MARBLES: Biorepository Upkeep and Infrastructure for Longitudinal Data Sharing for MARBLESR24ES028533 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Brittany D. Chambers Butcher, Rebecca Jean Schmidt · 2017 to 2026
$2.3M
BUILDS MARBLES: Biorepository Upkeep and Infrastructure for Longitudinal Data Sharing for MARBLESU24ES028533 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAMBERS BUTCHER, BRITTANY D., SCHMIDT, REBECCA JEAN · 2023 to 2025
$1.2M
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MR/S009310/1Medical Research Council MR/S036520/1NIEHS NIH HHS R24 ES028533NIEHS NIH HHS U24 ES028533
6 · The paper itself

Abstract

Circulating vitamin B12 concentrations during pregnancy are associated with offspring health. Foetal DNA methylation changes could underlie these associations. Within the Pregnancy And Childhood Epigenetics Consortium, we meta-analysed epigenome-wide associations of circulating vitamin B12 concentrations in mothers during pregnancy (

Indexed as

DNA MethylationEpigenomeBirth WeightChildEpigenesis, GeneticFemaleFetal BloodHumansInfant, NewbornPregnancyVitamin B 12Vitamin B 12cohort studyDNA methylationepidemiologymeta-analysisPACE consortiumVitamin B12

Identifiers

PMID37093107
PMCPMC10128528
OpenAlexW4366822091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.