ArticleJournal of veterinary internal medicine
Dynamic contrast-enhanced computed tomography in dogs with nasal tumors.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Case Report: Pyogranulomatous Panniculitis Mimicking an Invasive Subcutaneous Mass with Muscular Pseudo-Invasion in a Dog.Veterinary sciences · 2026Article
- Computed tomography perfusion in predicting radiation therapy response in dogs and a cat with head and neck tumors.Journal of veterinary internal medicine · 2026Article
- Cross-Sectional Radiological and Reconstructive Anatomy of the Paranasal Sinuses in Normal Mesaticephalic Dogs.Veterinary medicine and science · 2025Article
- Dynamic Computed Tomography for detecting pulmonary cysts in canine Paragonimiasis: a case report.The Journal of veterinary medical science · 2025Article
- Dynamic contrast-enhanced computed tomography in dogs with nasal tumors.Journal of veterinary internal medicineArticle
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundTreatment of nasal tumors in dogs is associated with high morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion.
objectivesTo assess perfusion parameters of nasal tumors (correlating with tumor type) before and during radiotherapy (RT) and find potential correlation with survival. ANIMALS: Twenty-four client-owned dogs with nasal tumors, including 16 epithelial tumors and 8 sarcomas.
methodsProspective cross-sectional study. All dogs had baseline DCECT to assess fractional vascular volume (BV), blood flow (BF), and transit time (TT). Thirteen dogs had repeat DCECT after 12 Gy of megavoltage RT. Survival times were calculated.
resultsMedian BV was 17.83 mL/100 g (range, 3.63-66.02), median BF was 122.63 mL/100 g/minute (range, 23.65-279.99), and median TT was 8.91 seconds (range, 4.57-14.23). Sarcomas had a significantly lower BF than adenocarcinomas (P = .002), carcinomas (P = .01), and other carcinomas (P = .001), and significantly lower BV than adenocarcinomas (P = .03) and other carcinomas (P = .004). Significant associations were found between epithelial tumors and sarcoma for change in tumor volume (P = .01), width (P = .004), and length (P = .02) in that epithelial tumors decreased in volume whereas sarcomas increased in volume. Perfusion parameters were not correlated with survival. CONCLUSIONS AND CLINICAL IMPORTANCE: Nasal sarcomas have lower BV and BF than nasal carcinomas, and sarcomas have a lower size reduction than carcinomas early on during RT. Baseline results and changes in perfusion parameters may not be correlated with survival.
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