Evidence map›Paper›PMID 37092591›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Bidirectionally Regulating Viral and Cellular Ferroptosis with Metastable Iron Sulfide Against Influenza Virus.

Xinyu Miao, Yinyan Yin, Yulian Chen, Wenhui Bi, Yuncong Yin, Sujuan Chen, Daxin Peng, Lizeng Gao, Tao Qin, Xiufan Liu

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Xinyu MiaoCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Yinyan YinCollege of Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Yulian ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Wenhui BiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Yuncong YinCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Sujuan ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Daxin PengCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.ORCID 0000-0001-6773-5149
Lizeng GaoCAS Engineering Laboratory for Nanozyme, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, P. R. China.
Tao QinCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Xiufan LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, 225009, P. R. China.
Yangzhou University · CNMinistry of Education · MVPoultry Research Institute · CNYangzhou Vocational University · CNChinese Academy of Sciences · CN

Funding

111 Project D18007Agricultural Science and Technology Independent Innovation Fund of Jiangsu Province CX(22)3004High-Level Talent Support Plan of Yangzhou University (2020)NO.28International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions NO.7Jiangsu Province University Outstanding Science and Technology Innovation Team Project (2021)NO.1Jiangsu Provincial Natural Science Fund for Excellent Young Scholars BK20200105Jiangsu Qinglan Project (2021) NO.11Key Research and Development Program of Social Development of Jiangsu Province BE2022774National Key Research and Development Program of China 2021YFD1800202National Natural Science Foundation of China 32172942National Natural Science Foundation of China Foundation of Innovative Research Group grant 22121003Priority Academic Program Development of Jiangsu Higher Education Institutions PAPDYangzhou University Interdisciplinary Research Foundation for Veterinary Medicine Discipline of Targeted Support yzuxk202004
6 · The paper itself

Abstract

Influenza virus with numerous subtypes and frequent variation limits the development of high-efficacy and broad-spectrum antiviral strategy. Here, a novel multi-antiviral metastable iron sulfides (mFeS) against various influenza A/B subtype viruses is developed. This work finds that mFeS induces high levels of lipid peroxidation and •OH free radicals in the conservative viral envelope, which depends on Fe

Indexed as

FerroptosisInfluenza A virusInfluenza A Virus, H1N1 SubtypeAnimalsAntiviral AgentsFerrous CompoundsMiceAntiviral AgentsFerrous Compoundsferrous sulfideferroptosisinfluenza virusmetastable iron sulfidestherapy

Identifiers

PMID37092591
PMCPMC10265104
OpenAlexW4366821619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.