Evidence map›Paper›PMID 37092543›Full record

ArticleCancer reports (Hoboken, N.J.)2023

Pathologically confirmed women's breast cancer: A descriptive study of Tunisian and Algerian series.

Farah Sassi, Meriem Ben Rekaya, Ayed Belarbi, Dalia Chilla, Nada Mansouri, Leila Achouri, Essia Saied, Reda Kassa, Linda Belhaj Kacem, Manel Ouezani and 3 more

Abstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Farah SassiDepartment of Pathology, Charles Nicolle Hospital Tunis, UR17ES15, Faculté de Médecine de Tunis, Université de Tunis El Manar, Tunis, Tunisia.ORCID 0000-0003-2078-6795
Meriem Ben RekayaDepartment of Pathology, Charles Nicolle Hospital Tunis, UR17ES15, Faculté de Médecine de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Ayed BelarbiDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Dalia ChillaDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Nada MansouriDepartment of Pathology, Military Hospital, Tunis, Tunisia.
Leila AchouriDepartment of Surgical Oncology, Regional Hospital of Jendouba, Jendouba, Tunisia.
Essia SaiedDepartment of Pathology, Charles Nicolle Hospital Tunis, UR17ES15, Faculté de Médecine de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Reda KassaDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Linda Belhaj KacemDepartment of Pathology, Charles Nicolle Hospital Tunis, UR17ES15, Faculté de Médecine de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Manel OuezaniDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Nadjiba DebabecheDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Fatima RebhiDepartment of Pathology, Douéra Hospital, Laboratoire de Recherche polymorphisme génétique No. 18, Université d'Alger 1, Alger Centre, Algeria.
Soumaya RammehDepartment of Pathology, Charles Nicolle Hospital Tunis, UR17ES15, Faculté de Médecine de Tunis, Université de Tunis El Manar, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer (BC) is the most frequent malignancy among women in Tunisia and Algeria. Clinical and pathological characteristics of this cancer among these populations are not widely reported. The aim of the study was to report clinical and pathological characteristics of women's BC in a Tunisian and Algerian series.

methodsPathologically confirmed 1089 BCs were gathered in the pathology departments of three Northern Tunisian hospitals: Tunis military, Charles Nicolle and Jendouba and in the pathology department of Alger Douera hospital between January 2015 and December 2020. Clinical and pathological findings of the two series: age, tumor size, histological type, grading according to Scarff-Bloom Richardson grading system, lymph node status at the time of diagnosis in axillary lymphadenectomy specimens and the immunohistochemical expression of estrogen and progesterone receptors (ER/PR), HER2 and Ki-67, were collected from the pathological reports.

resultsThe median age at diagnosis was 50 and 48 years in Tunisian and Algerian series, respectively (p = 0.016). The diagnosis of BC was made on surgical specimens (lumpectomy or mastectomy) in 373/491 (76%) cases of the Tunisian series and in 225/598 (37.6%) cases of the Algerian one. Median tumor size was 2.8 cm and 2.5 cm in Algerian and Tunisian series, respectively (p = 0.252). Invasive BCs not otherwise specified was observed in 440/481 (91.5%) BCs in Tunisian series and in 519/586 (88.6%) BCs in Algerian series. Axillary lymph node positive tumors were observed in 64.6% and 58.8% of Tunisian and Algerian women, respectively (p = 0.926). BCs were ER positive in 311/385 (80.8%) and 486/571 (85.1%) cases and HER2 positive in 86/283 (30.4%) and 60/385 (15.6%) cases of Tunisian and Algerian series, respectively.

conclusionsIn Tunisia and Algeria, BC has poor prognostic factors with large tumor sizes and high rates of lymph nodes involvement at diagnosis.

Indexed as

Breast NeoplasmsAdultAgedAged, 80 and overAlgeriaFemaleHumansLymph Node ExcisionLymph NodesMiddle AgedPrognosisTunisiaYoung AdultAlgeriabreast cancerimmunohistochemistrymolecular breast cancer subtypespathologyTunisia

Identifiers

PMID37092543
PMCPMC10440841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.