Evidence map›Paper›PMID 37092523›Full record

ArticlePathophysiology : the official journal of the International Society for Pathophysiology2023

The Expressions of NF-κB, COX-2, Sp1, and c-Jun in Pancreatic Ductal Adenocarcinoma and Their Associations with Patient Survival.

Kaka Renaldi, Marcellus Simadibrata, Nur Rahadiani, Diah Rini Handjari, Alida Roswita Harahap, Kuntjoro Harimurti, Nasrul Zubir, Lianda Siregar, Imelda Maria Loho, Evlina Suzanna and 7 more

Open access · goldAbstract read
In one paragraph

Article in Pathophysiology : the official journal of the International Society for Pathophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Use of Nonsteroidal Anti-Inflammatory Drugs and Pancreatic Cancer Risk in the Women's Health Initiative.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Observational
  5. Article
  6. Recent advances in drug delivery and targeting for the treatment of pancreatic cancer.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  7. Nephroprotective Activity ofDrug design, development and therapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Kaka RenaldiDoctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.ORCID 0000-0002-1092-9644
Marcellus SimadibrataDivision of Gastroenterology, Pancreatobiliary and Gastrointestinal Endoscopy, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Nur RahadianiDepartment of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.ORCID 0000-0003-2342-8133
Diah Rini HandjariDepartment of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Alida Roswita HarahapDoctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.
Kuntjoro HarimurtiDepartment of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Nasrul ZubirDivision of Gastroenterology, Department of Internal Medicine, Dr. M. Djamil Hospital, Padang 25171, Indonesia.
Lianda SiregarDivision of Gastroenterohepatology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.
Imelda Maria LohoDivision of Gastroenterohepatology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.
Evlina SuzannaDepartment of Anatomical Pathology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.
Bonita PrawirodihardjoDepartment of Anatomical Pathology, Fatmawati Central General Hospital, Jakarta 12430, Indonesia.
Heriawaty HidajatDepartment of Anatomical Pathology, Persahabatan Central General Hospital, Jakarta 13230, Indonesia.
Budi WidodoDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.
Alphania RahniayuDepartment of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.ORCID 0000-0002-5059-7875
Renaningtyas TambunDepartment of Anatomical Pathology, St. Carolus Hospital, Jakarta 10440, Indonesia.
Andy WilliamDepartment of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.ORCID 0000-0002-4706-6969
Dadang MakmunDivision of Gastroenterology, Pancreatobiliary and Gastrointestinal Endoscopy, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
University of Indonesia · IDDharmais Cancer Hospital · IDAirlangga University · IDFatmawati Hospital · ID

Funding

University of Indonesia NKB-1589/UN2.RST/HKP.05.00/2020
6 · The paper itself

Abstract

Chronic inflammation is a crucial driver of carcinogenesis in pancreatic ductal adenocarcinoma (PDAC). Several studies have investigated the prognostic significance of cyclooxygenase-2 (COX-2) expression in PDAC patients, obtaining conflicting results. Nuclear factor kappa-B (NF-κB), specificity protein 1 (Sp1), and c-Jun are known as the transcription factors of the

Indexed as

c−Juncyclooxygenase−2nuclear factor kappa−Bpancreatic neoplasmsSp1

Identifiers

PMID37092523
PMCPMC10123625
OpenAlexW4361004912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.