Evidence map›Paper›PMID 37092404›Full record

ArticleBiomimetics (Basel, Switzerland)2023

Textile Design of an Intervertebral Disc Replacement Device from Silk Yarn.

Michael Wöltje, Liesa Künzelmann, Basak Belgücan, Andreas S Croft, Benjamin Voumard, Stefan Bracher, Philippe Zysset, Benjamin Gantenbein, Chokri Cherif, Dilbar Aibibu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Michael WöltjeInstitute of Textile Machinery and High-Performance Material Technology, Technische Universität Dresden, 01602 Dresden, Germany.ORCID 0000-0002-5405-0981
Liesa KünzelmannInstitute of Textile Machinery and High-Performance Material Technology, Technische Universität Dresden, 01602 Dresden, Germany.
Basak BelgücanInstitute of Textile Machinery and High-Performance Material Technology, Technische Universität Dresden, 01602 Dresden, Germany.
Andreas S CroftTissue Engineering for Orthopaedic and Mechanobiology, Bone and Joint Program, Department for BioMedical Research (DBMR), Medical Faculty, University of Bern, 3008 Bern, Switzerland.ORCID 0000-0003-1472-1979
Benjamin VoumardARTORG Center for Biomedical Engineering Research, University of Bern, 3008 Bern, Switzerland.
Stefan BracherARTORG Center for Biomedical Engineering Research, University of Bern, 3008 Bern, Switzerland.
Philippe ZyssetARTORG Center for Biomedical Engineering Research, University of Bern, 3008 Bern, Switzerland.ORCID 0000-0002-4712-7047
Benjamin GantenbeinTissue Engineering for Orthopaedic and Mechanobiology, Bone and Joint Program, Department for BioMedical Research (DBMR), Medical Faculty, University of Bern, 3008 Bern, Switzerland.ORCID 0000-0002-9005-0655
Chokri CherifInstitute of Textile Machinery and High-Performance Material Technology, Technische Universität Dresden, 01602 Dresden, Germany.
Dilbar AibibuInstitute of Textile Machinery and High-Performance Material Technology, Technische Universität Dresden, 01602 Dresden, Germany.
Technische Universität Dresden · DEUniversity of Bern · CH

Funding

Swiss National Science Foundation # 310030E_192674/1
6 · The paper itself

Abstract

Low back pain is often due to degeneration of the intervertebral discs (IVD). It is one of the most common age- and work-related problems in today's society. Current treatments are not able to efficiently restore the full function of the IVD. Therefore, the aim of the present work was to reconstruct the two parts of the intervertebral disc-the annulus fibrosus (AF) and the nucleus pulposus (NP)-in such a way that the natural structural features were mimicked by a textile design. Silk was selected as the biomaterial for realization of a textile IVD because of its cytocompatibility, biodegradability, high strength, stiffness, and toughness, both in tension and compression. Therefore, an embroidered structure made of silk yarn was developed that reproduces the alternating fiber structure of +30° and -30° fiber orientation found in the AF and mimics its lamellar structure. The developed embroidered ribbons showed a tensile strength that corresponded to that of the natural AF. Fiber additive manufacturing with 1 mm silk staple fibers was used to replicate the fiber network of the NP and generate an open porous textile 3D structure that may serve as a reinforcement structure for the gel-like NP.

Indexed as

annulus fibrosusembroideryfiber-based additive manufacturingintervertebral discnucleus pulposussilk

Identifiers

PMID37092404
PMCPMC10123607
OpenAlexW4365145517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.