Evidence map›Paper›PMID 37092353›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2023

The role of affective temperaments in bipolar disorder: The solid role of the cyclothymic, the contentious role of the hyperthymic, and the neglected role of the irritable temperaments.

Elie G Karam, Dahlia Saab, Salam Jabbour, Georges E Karam, Elie Hantouche, Jules Angst

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. The anxious bipolar phenotype: clinical complexity and treatment response.International journal of bipolar disorders · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elie G KaramInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.ORCID 0000-0002-4681-8225
Dahlia SaabInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.ORCID 0000-0002-7966-0401
Salam JabbourInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Georges E KaramInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Elie HantoucheAnxiety & Mood Center, Paris, France.ORCID 0000-0002-3614-0342
Jules AngstUniversity of Zurich, Zurich, Switzerland.ORCID 0000-0002-5186-1690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present study is to evaluate the role of individual affective temperaments as clinical predictors of bipolarity in the clinical setting.

methodsThe affective temperaments of 1723 consecutive adult outpatients presenting for various symptoms to a university-based mental health clinical setting were assessed. Patients were administered the Hypomania Checklist-32 and the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego - Auto-questionnaire (TEMPS-A) and were diagnosed by psychiatrists according to the DSM-5 criteria. TEMPS-A scores were studied as both continuous and normalized categorical

resultsAt the multivariable level and taking into account all temperaments, the irritable temperament is a consistent predictor of bipolar I and bipolar II disorders. Cyclothymic temperament also played a strong role in bipolarity but more decisively so in bipolar II and substance-induced bipolarity. The hyperthymic temperament had no role in bipolar I or bipolar II disorder.

Indexed as

Bipolar DisorderAdultCyclothymic DisorderHumansIrritable MoodPersonality InventoryPsychometricsSurveys and QuestionnairesTemperamentAffective temperamentbipolar disordercyclothymic temperamenthyperthymic temperamentirritable temperament

Identifiers

PMID37092353
PMCPMC10228355

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.