Evidence map›Paper›PMID 37092316›Full record

ArticleThe Laryngoscope2023

Development of a Predictive Model for Persistent Dizziness Following Vestibular Schwannoma Surgery.

Krish Suresh, Mohamed A Elkahwagi, Alejandro Garcia, James G Naples, C Eduardo Corrales, Matthew G Crowson

Abstract read
In one paragraph

Article in The Laryngoscope, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krish SureshDepartment of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts, U.S.A.ORCID 0000-0001-7517-0280
Mohamed A ElkahwagiDepartment of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts, U.S.A.
Alejandro GarciaDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, U.S.A.ORCID 0000-0002-8204-8053
James G NaplesDepartment of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, U.S.A.
C Eduardo CorralesDepartment of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts, U.S.A.
Matthew G CrowsonDepartment of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, U.S.A.

Funding

RESEARCH TRAINING-MEDICAL INFORMATICS 90T15LM007092 · NLM · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Nils Gehlenborg · 1992 to 2026
$32.8M
NIH HHS T15LM007092-30NLM NIH HHS T15 LM007092
6 · The paper itself

Abstract

objectiveIn an era of vestibular schwannoma (VS) surgery where functional preservation is increasingly emphasized, persistent postoperative dizziness is a relatively understudied functional outcome. The primary objective was to develop a predictive model to identify patients at risk for developing persistent postoperative dizziness after VS resection.

methodsRetrospective review of patients who underwent VS surgery at our institution with a minimum of 12 months of postoperative follow-up. Demographic, tumor-specific, preoperative, and immediate postoperative features were collected as predictors. The primary outcome was self-reported dizziness at 3-, 6-, and 12-month follow-up. Binary and multiclass machine learning classification models were developed using these features.

resultsA total of 1,137 cases were used for modeling. The median age was 67 years, and 54% were female. Median tumor size was 2 cm, and the most common approach was suboccipital (85%). Overall, 63% of patients did not report postoperative dizziness at any timepoint; 11% at 3-month follow-up; 9% at 6-months; and 17% at 12-months. Both binary and multiclass models achieved high performance with AUCs of 0.89 and 0.86 respectively. Features important to model predictions were preoperative headache, need for physical therapy on discharge, vitamin D deficiency, and systemic comorbidities.

conclusionWe demonstrate the feasibility of a machine learning approach to predict persistent dizziness following vestibular schwannoma surgery with high accuracy. These models could be used to provide quantitative estimates of risk, helping counsel patients on what to expect after surgery and manage patients proactively in the postoperative setting. LEVEL OF EVIDENCE: 4 Laryngoscope, 133:3534-3539, 2023.

Indexed as

Neuroma, AcousticAgedDizzinessFemaleHeadacheHumansMaleRetrospective StudiesTreatment OutcomeVertigoacoustic neuroma (vestibular schwannoma)machine learningvertigo

Identifiers

PMID37092316
PMCPMC10593906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.