Evidence map›Paper›PMID 37092296›Full record

ArticleEpigenetics2023

Age-associated DNA methylation changes in

Marco Morselli, Ronan Bennett, Nikko-Ideen Shaidani, Marko Horb, Leonid Peshkin, Matteo Pellegrini

Open access · diamondAbstract read
In one paragraph

Article in Epigenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. State-of-the-Art Age Determination Methods for Amphibians and Reptiles.Animals : an open access journal from MDPI · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marco MorselliMolecular, Cell & Developmental Biology, UCLA, Los Angeles, CA, USA.ORCID 0000-0003-3351-5791
Ronan BennettMolecular, Cell & Developmental Biology, UCLA, Los Angeles, CA, USA.
Nikko-Ideen ShaidaniEugene Bell Center for Regenerative Biology and Tissue Engineering and National Xenopus Resource, Marine Biological Laboratory, Woods Hole, MA, USA.
Marko HorbEugene Bell Center for Regenerative Biology and Tissue Engineering and National Xenopus Resource, Marine Biological Laboratory, Woods Hole, MA, USA.ORCID 0000-0002-5067-0518
Leonid PeshkinEugene Bell Center for Regenerative Biology and Tissue Engineering and National Xenopus Resource, Marine Biological Laboratory, Woods Hole, MA, USA.ORCID 0000-0002-6420-848X
Matteo PellegriniMolecular, Cell & Developmental Biology, UCLA, Los Angeles, CA, USA.ORCID 0000-0001-9355-9564
Marine Biological Laboratory · USUniversity of California, Los Angeles · US

Funding

Resource CoreP40OD010997 · OD · MARINE BIOLOGICAL LABORATORY · PI Marko E Horb · 2012 to 2026
$13.1M
Systems Analysis of cell type differentiation in Xenopus developmentR01HD073104 · NICHD · HARVARD MEDICAL SCHOOL · PI KIRSCHNER, MARC WALLACE, PESHKIN, LEON · 2012 to 2022
$6.7M
Xenopus Mutant ResourceR24OD030008 · OD · MARINE BIOLOGICAL LABORATORY · PI Marko E Horb · 2020 to 2026
$6.0M
XenCAT: Xenopus Single Cell AtlasR24OD031956 · OD · HARVARD MEDICAL SCHOOL · PI PESHKIN, LEON · 2022 to 2025
$3.5M
NICHD NIH HHS R01 HD073104NIH HHS P40 OD010997NIH HHS R24 OD030008NIH HHS R24 OD031956
6 · The paper itself

Abstract

Age-associated changes in DNA methylation have been characterized across various animals, but not yet in amphibians, which are of particular interest because they include widely studied model organisms. In this study, we present clear evidence that the aquatic vertebrate species

Indexed as

DNA MethylationSulfitesAnimalsCpG IslandsMammalsSequence Analysis, DNAWhole Genome SequencingXenopusXenopus laevishydrogen sulfiteSulfitesDNA methylationEpigenetic clocktargeted bisulfite sequencingwhole-genome bisulfite sequencingXenopus

Identifiers

PMID37092296
PMCPMC10128463
OpenAlexW4366822080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.