Evidence map›Paper›PMID 37092129›Full record

ArticleJournal of inflammation research2023

Systemic Immune-Inflammation Index and Long-Term Mortality in Patients with Stroke-Associated Pneumonia.

Mengdi Xie, Kang Yuan, Xinyi Zhu, Jingjing Chen, Xiaohao Zhang, Yi Xie, Min Wu, Zhaojun Wang, Rui Liu, Xinfeng Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Pooled it
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  8. A Risk Prediction Model for MDRJournal of multidisciplinary healthcare · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mengdi Xie *Department of Neurology, Jinling Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Kang Yuan *Department of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.ORCID 0000-0002-4482-2503
Xinyi Zhu *Department of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.
Jingjing ChenDepartment of Neurology, Changhai Hospital, Navy Medical University, Shanghai, People's Republic of China.
Xiaohao ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-8916-8592
Yi XieDepartment of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.ORCID 0000-0001-8095-4856
Min WuDepartment of Neurology, Jinling Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0003-4485-975X
Zhaojun WangDepartment of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.
Rui LiuDepartment of Neurology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.
Xinfeng LiuDepartment of Neurology, Jinling Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-8182-9632
Nanjing General Hospital of Nanjing Military Command · CNNanjing Medical University · CNSecond Military Medical University · CNUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systemic immune inflammation has been investigated as a prognostic marker of different diseases. This study is designed to assess the association of systemic immune-inflammation index (SII) with long-term mortality of stroke-associated pneumonia (SAP) patients. Methods: Patients aged ≥18 years with SAP were selected from the Nanjing Stroke Registry Program in China. We retrospectively evaluated systemic immune-inflammation response with SII and pneumonia severity with the pneumonia severity index and the confusion, uremia, elevated respiratory rate, hypotension, and aged 65 years or older score. To explore the correlation between SII and mortality in SAP patients, multivariable Cox regressions and competing risk regressions were conducted. Mediation analysis was also performed to assess the role of pneumonia severity. Results: Among 611 patients in the SAP population, death occurred in 164 patients (26.8%) during the median follow-up of 3.0 (1.2-4.6) years. In multivariate analysis, higher SII scores could predict increased mortality in patients with SAP (adjusted hazard ratio 2.061; 95% confidence interval, 1.256-3.383; Conclusion: Our study displayed that SII was characterized in SAP patients with different prognoses. Elevated SII scores increased the risk of mortality. Further research is required for the clinical practice of the index among SAP patients.

Indexed as

Chinamortalitystroke-associated pneumoniasystemic immune-inflammation index

Identifiers

PMID37092129
PMCPMC10120842
OpenAlexW4366122010

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.