Evidence map›Paper›PMID 37091981›Full record

ArticleFrontiers in cell and developmental biology2023

Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.

Xiaoqing Xie, Pradeep Kumar Patnana, Daria Frank, Judith Schütte, Yahya Al-Matary, Axel Künstner, Hauke Busch, Helal Ahmed, Longlong Liu, Daniel R Engel and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Xiaoqing XieDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Pradeep Kumar PatnanaDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Daria FrankDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Judith SchütteDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Yahya Al-MataryDepartment of Dermatology, University Hospital Essen, Essen, Germany.
Axel KünstnerInstitute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Hauke BuschInstitute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
Helal AhmedDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Longlong LiuDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Daniel R EngelDepartment of Immunodynamics, Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany.
Ulrich DührsenDepartment of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany.
Frank RosenbauerInstitute for Molecular Tumor Biology, University Hospital Münster, Münster, Germany.
Nikolas Von BubnoffDepartment of Hematology and Oncology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Georg LenzDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Cyrus KhandanpourDepartment of Medicine A, Hematology, Oncology, and Pneumology, University Hospital Münster, Münster, Germany.
Essen University Hospital · DEUniversity Hospital Münster · DEUniversity of Lübeck · DEChongqing University · CNUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GFI1 is a transcriptional repressor and plays a pivotal role in regulating the differentiation of hematopoietic stem cells (HSCs) towards myeloid and lymphoid cells. Serial transplantation of

Indexed as

differentiationdose-dependentengraftmentGfi1HSC

Identifiers

PMID37091981
PMCPMC10113925
OpenAlexW4362640813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.