Evidence map›Paper›PMID 37091909›Full record

ArticleJournal of biomedical optics2023

Stable tissue-mimicking phantoms for longitudinal multimodality imaging studies that incorporate optical, CT, and MRI contrast.

Mengyang Zhao, Mingwei Zhou, Xu Cao, Jinchao Feng, Brian W Pogue, Keith D Paulsen, Shudong Jiang

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mengyang ZhaoDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.ORCID 0000-0001-5952-1263
Mingwei ZhouDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.
Xu CaoDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.
Jinchao FengBeijing University of Technology, Beijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing, China.ORCID 0000-0001-5603-8874
Brian W PogueDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.ORCID 0000-0002-9887-670X
Keith D PaulsenDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.
Shudong JiangDartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States.ORCID 0000-0001-7396-7886
Dartmouth College · USBeijing University of Technology · CN

Funding

Concurrent Optical Spectroscopy and Breast MRI to Improve Diagnosis without Contrast InjectionR01EB027098 · NIBIB · DARTMOUTH COLLEGE · PI Shudong Jiang, KEITH D. PAULSEN · 2019 to 2026
$3.3M
Monitoring Neoadjuvant Chemotherapy Responses with NIR TomographyR01CA176086 · NCI · DARTMOUTH COLLEGE · PI JIANG, SHUDONG · 2014 to 2018
$2.0M
NCI NIH HHS R01 CA176086NIBIB NIH HHS R01 EB027098
6 · The paper itself

Abstract

Significance: Tissue phantoms that mimic the optical and radiologic properties of human or animal tissue play an important role in the development, characterization, and evaluation of imaging systems. Phantoms that are easily produced and stable for longitudinal studies are highly desirable. Aim: A new type of long-lasting phantom was developed with commercially available materials and was assessed for fabrication ease, stability, and optical property control. Magnetic resonance imaging (MRI) and x-ray computed tomography (CT) contrast properties were also evaluated. Approach: A systematic investigation of relationships between concentrations of skin-like pigments and composite optical properties was conducted to realize optical property phantoms in the red and near-infrared (NIR) wavelength range that also offered contrast for CT and MRI. Results: Phantom fabrication time was Conclusions: The phantoms described here mimic optical properties of soft tissue and are suitable for multimodality imaging studies involving CT or MRI without adding secondary contrast agents.

Indexed as

Contrast MediaTomography, OpticalAnimalsHumansMagnetic Resonance ImagingMultimodal ImagingPhantoms, ImagingTomography, X-Ray ComputedContrast Mediamultimodality imagingoptical propertyspectroscopytissue phantom

Identifiers

PMID37091909
PMCPMC10118137
OpenAlexW4366547907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.