Evidence map›Paper›PMID 37091846›Full record

ArticleFrontiers in endocrinology2023

Mini-puberty testosterone and infant autistic traits.

Alex Tsompanidis, Sarah Hampton, Ezra Aydin, Carrie Allison, Rosemary Holt, Simon Baron-Cohen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alex TsompanidisAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Sarah HamptonYork Trials Unit, University of York, York, United Kingdom.
Ezra AydinVagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Carrie AllisonAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Rosemary HoltAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Simon Baron-CohenAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBColumbia University · USUniversity of York · GB

Funding

Wellcome TrustWellcome Trust 214322\Z\18\Z
6 · The paper itself

Abstract

Background: Levels of steroid hormones in the first three months of life, a period referred to as 'mini-puberty', are one of the earliest physiological differences between typical males and females postnatally. Autistic traits also show consistent typical sex differences in later infancy, after the 18 Methods: The 'Cambridge Human Imaging and Longitudinal Development Study' (CHILD) is a prospective enriched cohort study in Cambridge, UK. It includes physiological measurements in early infancy, as well as neurodevelopmental follow-ups over the first two years of life. A subset of the cohort also includes children with a family history of autism (a diagnosed parent or sibling). Salivary testosterone levels were assessed at two time-points, just after the 2 Results: Salivary testosterone levels were significantly higher during 'mini-puberty' in the 2 Conclusion: Both male and female infants have elevated levels of salivary testosterone during mini-puberty but in this relatively small sample this was not associated with their later autistic traits at 18 months or their family history of autism. This suggests that

Indexed as

Autistic DisorderTestosteroneCohort StudiesFemaleHumansInfantMalePregnancyProspective StudiesPubertyTestosteroneautismautistic traitsinfantlongitudinalmini-pubertytestosterone

Identifiers

PMID37091846
PMCPMC10113441
OpenAlexW4362626068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.