ReviewThe Saudi dental journal2023
Chemomechanical caries removal methods: A literature review.
Review in The Saudi dental journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- One-year clinical and radiographic evaluation of young permanent molars treated with brix 3000 vs. papacárie duo: a randomized controlled clinical trial.BMC oral health · 2025Trial
- Comparative evaluation of BRIX3000 and Carisolv in chemomechanical caries removal in immature permanent first molars: a randomized controlled trial.BMC oral health · 2025Trial
- The effectiveness of Carie-Care™, chemomechanical caries removal technique in primary teeth: randomized controlled clinical trial.BMC oral health · 2023Trial
- Caries removal efficiency and minimally invasive potential of SmartPrep burs, Brix 3000, and excavus: A micro-computed tomography comparative study.Journal of conservative dentistry and endodontics · 2026Article
- Microbial Composition of Carious Dentin and the Impact of Minimally Invasive Excavation Techniques: A Narrative Review.International journal of molecular sciences · 2026Review
- Effects and Properties of Deproteinizing Methods in Dentin: A Comprehensive Narrative Review.Journal of functional biomaterials · 2026Review
- Clinical and Biological Evaluation of Chemo-Mechanical Caries Excavation with Brix 3000 in Primary Molars: An 18-Month Prospective Study.Medicina (Kaunas, Lithuania) · 2026Article
- Non-Operative, Micro- and Minimally Invasive Methods for Caries Treatment-A Narrative Review.Journal of clinical medicine · 2026Review
- Concept and techniques for minimal invasive restorative dentistry: A review.Bioinformation · 2026Article
- Fluorescence as a Quantitative Indicator of Cariogenic Bacteria During Chemo-Mechanical Caries Excavation with BRIX 3000 in Primary Teeth.Journal of functional biomaterials · 2025Article
- Article
- Histological Evaluation of Chemo Mechanical Caries Removal with a Babaco-Based Formulation Gel.Gels (Basel, Switzerland) · 2025Article
- Comparative study for assessment of two different minimally invasive caries removal techniques.BMC oral health · 2025Article
- Effect of enzymatic chemo-mechanical agents on adhesion of composite resin to dentin of permanent teeth: an in vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Article
- Antimicrobial Efficacy of Chemomechanical Carie Removal Agents-A Systematic Integrative Review.Biomedicines · 2024Review
- Association of Papacarie Duo® and low-level laser in antimicrobial photodynamic therapy (aPDT).Lasers in medical science · 2024Article
- Pain Perception During Minimally Invasive Caries Removal in Children: A Randomized Clinical Trial Comparing Chemo-Mechanical Caries Removal.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To provide dental practitioners and researchers with a comprehensive review of the historical development, chemical composition, mechanisms of action, advantages, and drawbacks of different chemomechanical caries removal (CMCR) agents. Methods: An electronic search was performed for all articles published on CMCR agents in various databases, including the Web of Science, PubMed, Cochrane, Scopus, and Google Scholar bibliographic databases, from January 1, 1975, to July 31, 2022. Results: Records were identified using the following search terms: Brix3000, Carie-Care, Caridex, Carisolv, chemomechanical caries removal, conventional surgical method, and Papacárie. A total of 171 articles were screened based on the titles and abstracts, of which 126 were deemed eligible for inclusion after duplicates were removed. Following a manual search of the reference list, eight articles were added. Articles were then excluded for other reasons, such as being written before 1975, being written in a language other than English, and the non-availability of the full text. Overall, 120 articles were included in the analysis (literature reviews [n = 27], systematic reviews [n = 8], research articles [n = 82], case reports [n = 3]). Conclusion: CMCR is a potential method of caries control in the future as an alternative to the conventional surgical approach in standard dentistry applications. It is more widely accepted, less painful, and has comparable efficacy to the conventional surgical method. Clinical significance: A continuous trend among manufacturers has been observed since 1975 to reduce the drawbacks of CMCR agents. Moreover, evidence-based minimally invasive techniques, including CMCR agents that require minimal or no aerosol-generating procedures, are preferred while measures to control the spread of coronavirus disease are in force.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.