Evidence map›Paper›PMID 37091146›Full record

SynthesisFrontiers in oncology2023

Erectile function, urinary continence and oncologic outcomes of neurovascular bundle sparing robot-assisted radical prostatectomy for high-risk prostate cancer: A systematic review and meta-analysis.

Yang Liu, Xian-Zhong Deng, Jiao Qin, Zhi Wen, Yu Jiang, Jing Huang, Chong-Jian Wang, Cai-Xia Chen, Li Wang, Kun-Peng Li and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Long-term function and oncologic outcomes following nerve spare or wide resection during radical prostatectomy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yang LiuDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Xian-Zhong DengDepartment of Urology, Chengdu Xinhua Hospital Affiliated to North Sichuan Medical College, Chengdu, China.
Jiao QinDepartment of Anesthesia, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Zhi WenDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Yu JiangDepartment of Radiate, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Jing HuangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Chong-Jian WangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Cai-Xia ChenDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Li WangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Kun-Peng LiDepartment of Urology, Lanzhou University Second Hospital, Lanzhou, China.
Jia-Hao WangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Xue-Song YangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Affiliated Hospital of North Sichuan Medical College · CNChengdu Medical College · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The nerve-sparing (NS) effect of robot-assisted radical prostatectomy (RARP) on patients with a high-risk prostate cancer remains unclear. The objective of this study was to compare the urinary continence, erectile function and oncology outcomes of the nerve-sparing and non-nerve-sparing (NNS) group during RARP surgeries. Methods: We systematically searched databases including PubMed, Embase, Cochrane Library and Web of Science to identify relevant studies published in English up to December 2022. Newcastle-Ottawa Scale (NOS) was used as a quality evaluation tool to evaluate the quality of the literature parameters involved, including urinary continence, erectile function and oncologic outcomes, which were compared using the Stata 15.1 software (StataSE, USA). Results: A total of 8 cohort studies involving 2499 patients were included. A meta-analysis of results showed that the NS group was beneficial to the recovery of urinary continence (RR 0.46, 95%CI 0.22, 0.96; p=0.045<0.05) and erectile function (RR 0.32, 95%CI 0.16, 0.63; p=0.001<0.05) 12 months after surgeries, which showed a better oncological outcome (RR 1.31, 95%CI 1.01, 1.69; p=0.01<0.05). Conclusions: The current study results indicate that intraoperative NS during RARP is beneficial to long-term postoperative functional recovery and tumor prognosis of patients with high-risk prostate cancers. Due to interstudy interferences, the results should be interpreted with caution. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022384647.

Indexed as

continencehigh-risk prostate cancermeta-analysisneurovascular bundleoutcomesrobot-assisted radical prostatectomy

Identifiers

PMID37091146
PMCPMC10113629
OpenAlexW4362622366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.