Evidence map›Paper›PMID 37091039›Full record

ArticleInternational journal of molecular and cellular medicine2022

Novel Variant Identified in the Enhancer Region of Host Transcription Factor, BRN3A, is a Significant Risk Factor for HPV-Induced Uterine Cervix Cancer.

Anand Prakash, Biswa Pratim Das Purkayastha, Shikha Srivastava, Sunanda Chaturvedi, Akhtar Ali, Dau Dayal Aggarwal, Jagat Kumar Roy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular and cellular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anand PrakashDepartment of Zoology, Banaras Hindu University, Varanasi, India.
Biswa Pratim Das PurkayasthaDepartment of Zoology, Banaras Hindu University, Varanasi, India.
Shikha SrivastavaDepartment of Zoology, Banaras Hindu University, Varanasi, India.
Sunanda ChaturvediHomi Bhabha Cancer Hospital & Research Centre, Varanasi, India.
Akhtar AliCentre for Genetic Disorders, Banaras Hindu University, Varanasi, India.
Dau Dayal AggarwalDepartment of Zoology, Banaras Hindu University, Varanasi, India.
Jagat Kumar RoyDepartment of Zoology, Banaras Hindu University, Varanasi, India.
Banaras Hindu University · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the HPV-mediated cervical cancers, cellular factor BRN3A has gained considerable attention due to its role in promoting an anti-apoptotic cellular environment and in facilitating epitheliotropic transformations of the host. The majority of previous studies looked at BRN3A's molecular characteristics; however, the possibility of genetic variations in BRN3A's auto-regulatory region in relation to cervical cancer risk has been underestimated until now. In a retrospective study in the Eastern UP population, India, we detected genetic variations in the cis-regulatory proximal enhancer region located around 5.6 kb upstream of transcription start site of

Indexed as

BRN3ABRN3A proximal enhancer regionCervical cancerg. 6016 3379A >GHPVIndia

Identifiers

PMID37091039
PMCPMC10116355
OpenAlexW4366821947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.