Evidence map›Paper›PMID 37090926›Full record

ArticleFrontiers in pediatrics2023

Association of interleukin-4, interleukin-13 gene polymorphisms, HLA-DQ and DR genotypes with genetic susceptibility of type-1 Diabetes Mellitus in Kuwaiti children.

Mohammad Z Haider, Maysoun Al Rushood, Hind Alsharhan, Majedah A Rasoul, Maria Al-Mahdi, Hessa Al-Kandari

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Mohammad Z HaiderDepartment of Pediatrics, College of Medicine, Kuwait University, Jabriya, Kuwait.
Maysoun Al RushoodDepartment of Pediatrics, College of Medicine, Kuwait University, Jabriya, Kuwait.
Hind AlsharhanDepartment of Pediatrics, College of Medicine, Kuwait University, Jabriya, Kuwait.
Majedah A RasoulDepartment of Pediatrics, College of Medicine, Kuwait University, Jabriya, Kuwait.
Maria Al-MahdiDepartment of Pediatrics, Al-Adan Hospital, Adan, Kuwait.
Hessa Al-KandariDepartment of Pediatrics, Farwaniya Hospital, Farwaniya, Kuwait.
Kuwait University · KWAdan Hospital · KWDasman Diabetes Institute · KWFarwaniya Hospital · KWMubarak Al Kabeer Hospital · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Type-1 diabetes mellitus (T1DM) is a complex multifactorial disease with an autoimmune etiology and is thought to result from an interaction between genetic and non-genetic factors. Cytokines play a crucial role in the pathogenesis of autoimmune diseases due to their effector and regulatory functions in immune responses. Interleukin-4 (IL4) and Interleukin-13 (IL13) are anti-inflammatory cytokines and are considered as important mediators in pathology of the autoimmune diseases. Methods: We have determined the genotype frequency of Results: The CC genotype of Conclusions: We have identified the association of

Indexed as

cytokine geneHLAKuwaitpolymorphismtype 1 diabetes mellitus

Identifiers

PMID37090926
PMCPMC10117788
OpenAlexW4362671723

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.