ArticleLaryngoscope investigative otolaryngology2023
Cranial nerve palsy prevalence and associated factors in patients with malignant otitis externa.
Article in Laryngoscope investigative otolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Malignant Otitis Externa in Central Australia: A 15-Year Retrospective Review Between 2009 and 2024.The Medical journal of Australia · 2026Observational
- Facial Nerve Palsy in Malignant Otitis Externa Hospitalizations: Outcomes and Risk Factors.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Case Report: When infection mimics autonomic failure: postural hypotension secondary to skull base osteomyelitis.Frontiers in medicine · 2026Article
- Fungal necrotizing otitis externa; challenges in diagnosis and therapy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Article
- Patient cases with malignant otitis externa at the university clinic of Ludwig Maximilians University Munich from 2009 until 2020.Scientific reports · 2025Article
- Evaluation of the clinical and radiological features of patients with Malignant otitis externa (MOE).BMC infectious diseases · 2025Article
- Are artificial intelligence large language models a reliable tool for difficult differential diagnosis? An a posteriori analysis of a peculiar case of necrotizing otitis externa.Clinical case reports · 2023Article
- Cranial nerve palsy prevalence and associated factors in patients with malignant otitis externa.Laryngoscope investigative otolaryngology · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To identify the prevalence of cranial nerve (CN) palsy and its associated factors in malignant otitis externa (MOE). Methods: In a retrospective study, records of MOE patients from 2011 to 2014 were reviewed. MOE and CN involvement were evaluated based on patient demographics, clinical, and paraclinical data. Results: Overall, 119 MOE patients with a mean age of 65.9 ± 11.3 were included. 69.7% were male, and 63.0% had a history of diabetes. The most common symptoms and signs were otalgia (97.5%), otorrhea (44.5%), and ear canal erythema/edema (24.4%). Thirty-three patients (27.7%) had CN involvement. The facial nerve was mostly involved (26.1%). Skull base osteomyelitis (SBO) was present in 59 patients. When excluding patients younger than 30 and older than 80, age decade was correlated with CN palsy. 66.9% of patients with CN palsy and 65.6% without CN palsy were male, which was significantly different. The following factors were not significantly different between patients with and without CN palsy: Comorbidities, signs and symptoms, diagnostic delay, erythrocyte sedimentation rate level, fasting blood sugar, hemoglobin A1c level, antifungal therapy, hospitalization duration, and SBO on imaging. Tinnitus was correlated with SBO evidence on imaging (specificity: 96.7%). Conclusion: CN involvement occurs in about three out of 10 MOE patients. Male gender and advanced age may be related to a higher incidence rate of CN palsy. Tinnitus can be a specific indicator of SBO. These findings could help in better decision-making for early interventions. Level of Evidence: 4.
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