Evidence map›Paper›PMID 37090868›Full record

ArticleLaryngoscope investigative otolaryngology2023

Differences in pharyngeal swallow event timing: Healthy aging, Parkinson disease, and amyotrophic lateral sclerosis.

Pooja Gandhi, Emily K Plowman, Catriona M Steele

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Reference Values for Videofluoroscopic Measures of Swallowing: An Update.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Pooja GandhiSwallowing Rehabilitation Research Laboratory KITE Research Institute-University Health Network Toronto Ontario Canada.ORCID https://orcid.org/0000-0003-0297-7555
Emily K PlowmanAerodigestive Research Core-University of Florida Gainesville Florida United States.
Catriona M SteeleSwallowing Rehabilitation Research Laboratory KITE Research Institute-University Health Network Toronto Ontario Canada.
University Health Network · CAUniversity of Florida · US

Funding

Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of SwallowingR01AG077481 · NIA · UNIVERSITY HEALTH NETWORK · PI Emily Kate Plowman, Catriona Margaret Steele · 2022 to 2026
$4.3M
Tongue-pressure timing for liquid flow detection and control in swallowingR01DC011020 · NIDCD · UNIVERSITY HEALTH NETWORK · PI STEELE, CATRIONA MARGARET · 2010 to 2020
$2.9M
Landis Outstanding Mentor Award SupplementR01NS100859 · NINDS · UNIVERSITY OF FLORIDA · PI PLOWMAN, EMILY KATE · 2017 to 2021
$2.0M
NIA NIH HHS R01 AG077481NIDCD NIH HHS R01 DC011020NINDS NIH HHS R01 NS100859
6 · The paper itself

Abstract

Objective: The pharyngeal phase of swallowing involves a coordinated sequence of events. Event durations may be prolonged in people with Parkinson disease (PwPD), and amyotrophic lateral sclerosis (PwALS); however, the cumulative effect of these changes is unexplored. We compared event latencies relative to hyoid burst (HYB) (time zero) to understand differences in deglutatory event timing. We hypothesized PwPD and PwALS would display similarly prolonged cumulative pharyngeal phase durations compared to healthy controls, with greater prolongations with increasing bolus viscosity. Method: We retrospectively evaluated videofluoroscopic data of healthy adults ( Results: In PwPD, significantly prolonged latencies were observed on thin liquid boluses compared to healthy controls. Latencies to all post-HYB events were significantly prolonged except for maximum upper esophageal sphincter distension. In PwALS, significantly prolonged latencies for events preceding and following HYB were noted on all consistencies compared to healthy controls and PwPD. Conclusion: In PwPD, event latencies for multiple components of the swallowing sequence were prolonged culminating in overall prolongation of the pharyngeal phase on thin liquid. A similar pattern, but with significantly greater prolongation, was seen in the PwALS, and extended to swallows of all liquid consistencies.

Indexed as

amyotrophic lateral sclerosisdeglutitiondeglutition disorders Parkinson disease

Identifiers

PMID37090868
PMCPMC10116960
OpenAlexW4318982866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.