Evidence map›Paper›PMID 37090767›Full record

ArticleFrontiers in nutrition2023

Oral pyruvate prevents high-intensity interval exercise-induced metabolic acidosis in rats by promoting lactate dehydrogenase reaction.

Kaixuan Che, Yanping Yang, Jun Zhang, Lin Feng, Yan Xie, Qinlong Li, Junqiang Qiu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kaixuan CheDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Yanping YangDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Jun ZhangDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Lin FengDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Yan XieDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Qinlong LiDepartment of Exercise Physiology, Exercise Science School, Beijing Sport University, Beijing, China.
Junqiang QiuDepartment of Exercise Biochemistry, Exercise Science School, Beijing Sport University, Beijing, China.
Beijing Sport University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: There is no denying the clinical benefits of exogenous pyruvate in the treatment of pathological metabolic acidosis. However, whether it can prevent exercise physiological metabolic acidosis, delay the occurrence of exercise fatigue, and improve the beneficial effects of exercise and its internal mechanism remain unclear. Methods: We randomly divided 24 male SD rats into 3 groups: one group was a control without exercise (CC, Results: Pyruvate supplementation significantly reversed the decrease of pHe, BE, HCO Discussion: This study provides compelling evidence that oral pyruvate attenuates HIIE-induced intracellular and extracellular acidification, possibly due to increased activity of LDHA, which promotes the absorption of H

Indexed as

glycolysishigh-intensity interval exerciselactate dehydrogenase reactionmetabolic acidosisredox

Identifiers

PMID37090767
PMCPMC10117856
OpenAlexW4362673175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.