ReviewFrontiers in immunology2023
The immunomodulatory mechanisms for acupuncture practice.
Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
106 citing papers in PubMed, 10 syntheses or guidelines pooled it, 148 citations in OpenAlex.
- Efficacy of acupuncture in managing radiotherapy/chemotherapy-induced oral mucositis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Experimental Evidence on Acupuncture Targeting Ferroptosis for Neurological Function Improvement in Cerebral Stroke: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Acupuncture combined with language training for aphasia in children with cerebral palsy: a systematic review with meta-analysis and trial sequential analysis.Frontiers in neurology · 2025Pooled it
- Efficacy of Acupuncture in Managing Radiation-Induced Xerostomia: An Updated Meta-Analysis.International journal of medical sciences · 2025Pooled it
- Acupuncture combined with Chinese herbal medicine versus Chinese herbal medicine alone to improve clinical efficacy in treating endometriosis-associated pain: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- A systematic review and meta-analysis of the effect of acupuncture therapy on the symptoms and immune indicators of ankylosing spondylitis.Frontiers in neurology · 2025Pooled it
- Efficacy and safety of acupuncture for chronic spontaneous urticaria: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- How effective is acupuncture in treating hot flashes in breast cancer patients? A systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- A strategic study of acupuncture for diabetic kidney disease based on meta-analysis and data mining.Frontiers in endocrinology · 2024Pooled it
- Efficacy and safety of acupuncture for painful diabetic neuropathy: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Laser acupuncture improves cortical excitability and behavioural performance in healthy individuals: a randomized controlled trial.BMC complementary medicine and therapies · 2026Trial
- Acupuncture combined with immunotherapy for recurrent and metastatic cervical cancer: a pilot RCT protocol.Frontiers in oncology · 2026Trial
- Electroacupuncture for juvenile idiopathic arthritis: clinical efficacy and its role in modulating pyroptosis and autophagy pathways.Clinical rheumatology · 2025Trial
- Driving Drugs Deeper: Force-Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Differential physiological responses to electroacupuncture at ST36 and SP6 in CFA-induced inflammatory arthritis: serum metabolomic evidence for acupoint-specific redox regulation.The journal of physiological sciences : JPS · 2026Article
- Application of Chinese Medicine in Treatment of Ulcerative Colitis and Elucidation of Relevant Mechanisms.Chinese journal of integrative medicine · 2026Review
- Predictive Value of the Systemic Immune-Inflammation Index for the Clinical Efficacy of Acupuncture and Exercise Rehabilitation in Knee Osteoarthritis: A Retrospective Study.Immunity, inflammation and disease · 2026Observational
- Complementary and Alternative Medicine in Oncology: A Concise Review of Utilization, Evidence, and Integration Challenges.Cancer reports (Hoboken, N.J.) · 2026Review
- Differential Improvement in Memory and Executive Functions: Personalized Exercise versus Acupuncture for Mild Cognitive Impairment in Stroke-prone Individuals.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Secretome as a novel regenerative strategy for atopic dermatitis: a comprehensive review.Stem cell research & therapy · 2026Review
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The system physiology approaches that emerge in western countries in recent years echo the holistic view of ancient Traditional Chinese Medicine (TCM) practices that deal with the root, rather than only the symptoms of diseases. Particularly, TCM practices, including acupuncture, emphasize the mobilization of self-healing mechanisms to bring back body homeostasis. Acupuncture has been practiced for over two thousand years to modulate body physiology
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.