Evidence map›Paper›PMID 37090713›Full record

ArticleFrontiers in immunology2023

N-acetyl-L-cysteine alleviated the oxidative stress-induced inflammation and necroptosis caused by excessive NiCl

Xintong Zhang, Lihua Xu, Wenxue Ma, Bendong Shi, Qiaohan Liu, Yinghao Song, Cheng Fang, Pinnan Liu, Senqiu Qiao, Jingzeng Cai and 1 more

Open access · goldAbstract read
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In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xintong ZhangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Lihua XuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Wenxue MaCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Bendong ShiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Qiaohan LiuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Yinghao SongCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Cheng FangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Pinnan LiuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Senqiu QiaoCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Jingzeng CaiCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Ziwei ZhangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Northeast Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Nickel (Ni) is widely used in industrial manufacturing and daily life due to its excellent physical and chemical properties. However, Ni has the potential to harm animals' immune system, and spleen is a typical immune organ. Therefore, it is crucial to understand the mechanism of NiCl Methods: In this experiment, mice spleen lymphocytes were used as the research object. We first measured the degree of oxidative stress, inflammation, and necroptosis caused by different NiCl Results: Our findings demonstrated that NiCl Discussion: Our findings showed that NiCl

Indexed as

AcetylcysteineAntioxidantsAnimalsHydrogen PeroxideInflammationLymphocytesMiceNecroptosisOxidative StressReactive Oxygen SpeciesRNA, MessengerSpleenTumor Necrosis Factor-alphaAcetylcysteineAntioxidantsHydrogen PeroxideReactive Oxygen SpeciesRNA, MessengerTumor Necrosis Factor-alphainflammationmice spleen lymphocytesnecroptosisNiCl2oxidative stress

Identifiers

PMID37090713
PMCPMC10117970
OpenAlexW4362671169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.