Evidence map›Paper›PMID 37090668›Full record

ArticlebioRxiv : the preprint server for biology2023

Lassa virus NP DEDDh 3'-5' exoribonuclease activity is required for optimal viral RNA replication and mutation control.

Cheng Huang, Emily Mantlo, Slobodan Paessler

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Cheng HuangDepartment of Pathology, Galveston National Laboratory and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0001-5402-353X
Emily MantloDepartment of Pathology, Galveston National Laboratory and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
Slobodan PaesslerDepartment of Pathology, Galveston National Laboratory and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
The University of Texas Medical Branch at Galveston · USSUNY Upstate Medical University · US

Funding

Regulatory Compliance Core - Galveston National Laboratory BSL4 OperationsUC7AI094660 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Gene Garrard Olinger · 2011 to 2026
$208.8M
Recombinant life attenuated vaccine against Argentine hemorrhagic feverR01AI093445 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI DE LA TORRE, JUAN C., PAESSLER, SLOBODAN · 2011 to 2015
$4.6M
Sequelae of Lassa FeverR01AI129198 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PAESSLER, SLOBODAN · 2018 to 2022
$3.9M
Mechanism of Lassa fever virus Z protein in immune suppression and viral virulenceR01AI131586 · NIAID · UNIVERSITY OF MINNESOTA · PI LIANG, YUYING, LY, HINH · 2017 to 2021
$3.8M
Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Novel Function(s) of Arenavirus NP ExoribonucleaseR21AI166985 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI HUANG, CHENG · 2022 to 2023
$440k
NIAID NIH HHS R01 AI093445NIAID NIH HHS R01 AI129198NIAID NIH HHS R01 AI131586NIAID NIH HHS R21 AI166985NIAID NIH HHS T32 AI060549NIAID NIH HHS UC7 AI094660
6 · The paper itself

Abstract

Lassa virus (LASV), a mammarenavirus from

Identifiers

PMID37090668
PMCPMC10120729
OpenAlexW4365449922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.