Evidence map›Paper›PMID 37090586›Full record

ArticlebioRxiv : the preprint server for biology2024

Defective pgsA contributes to increased membrane fluidity and cell wall thickening in S. aureus with high-level daptomycin resistance.

Christian D Freeman, Tayte Hansen, Ramona Urbauer, Brian J Wilkinson, Vineet K Singh, Kelly M Hines

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christian D FreemanDepartment of Chemistry, University of Georgia, Athens, GA, USA.ORCID 0000-0003-2258-2905
Tayte HansenDepartment of Microbiology and Immunology, A.T. Still University of Health Sciences, Kirksville, MO, USA.
Ramona UrbauerDepartment of Chemistry, University of Georgia, Athens, GA, USA.
Brian J WilkinsonSchool of Biological Sciences, Illinois State University, Normal, IL, USA.
Vineet K SinghDepartment of Microbiology and Immunology, A.T. Still University of Health Sciences, Kirksville, MO, USA.
Kelly M HinesDepartment of Chemistry, University of Georgia, Athens, GA, USA.ORCID 0000-0001-9125-5268
University of Georgia · USA.T. Still University · USIllinois State University · US

Funding

Impacts of host lipid composition on antimicrobial susceptibilities of Staphylococcus aureusR01AI173144 · NIAID · UNIVERSITY OF GEORGIA · PI Kelly M. Hines · 2023 to 2026
$1.8M
Elucidating altered lipid pathways in daptomycin-resistant pathogensK22AI143919 · NIAID · UNIVERSITY OF GEORGIA · PI HINES, KELLY M. · 2020 to 2021
$269k
NIAID NIH HHS K22 AI143919NIAID NIH HHS R01 AI173144
6 · The paper itself

Abstract

Daptomycin is a membrane-targeting last-resort antimicrobial therapeutic for the treatment of infections caused by methicillin- and/or vancomycin-resistant

Indexed as

branched fatty acidsdaptomycinlipidomicsliquid chromatography-mass spectrometrymembrane fluiditymprFpgsAStaphylococcus aureusyycG

Identifiers

PMID37090586
PMCPMC10120677
OpenAlexW4365148089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.