Evidence map›Paper›PMID 37090479›Full record

ArticleMolecular therapy. Methods & clinical development2023

Capsid-modified adeno-associated virus vectors as novel vaccine platform for cancer immunotherapy.

Ann-Christin Franke, Romain Hardet, Lisa Prager, Martin Bentler, Mélanie Demeules, Philipp John-Neek, Nico Martin Jäschke, Teng Cheong Ha, Ulrich Thorsten Hacker, Sahil Adriouch and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. AAV for ovarian cancer gene therapy.Cancer gene therapy · 2025
    Review
  6. Review
  7. Review
  8. Unlocking cancer vaccine potential: What are the key factors?Human vaccines & immunotherapeutics · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ann-Christin FrankeInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Romain HardetUniversity of Rouen, INSERM, U1234, Pathophysiology Autoimmunity and Immunotherapy (PANTHER), Normandie University, 76000 Rouen, France.
Lisa PragerInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Martin BentlerInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Mélanie DemeulesUniversity of Rouen, INSERM, U1234, Pathophysiology Autoimmunity and Immunotherapy (PANTHER), Normandie University, 76000 Rouen, France.
Philipp John-NeekInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Nico Martin JäschkeInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Teng Cheong HaInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Ulrich Thorsten HackerDepartment of Medicine II, University Cancer Center Leipzig (UCCL), University of Leipzig Medical Center, 04103 Leipzig, Germany.
Sahil AdriouchUniversity of Rouen, INSERM, U1234, Pathophysiology Autoimmunity and Immunotherapy (PANTHER), Normandie University, 76000 Rouen, France.
Hildegard BüningInstitute for Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DENormandie Université · FRUniversité de Rouen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy has significantly improved treatment outcomes in various cancer entities. To enhance immunogenicity and efficacy, and to further broaden its applicability, co-administration of anti-tumor vaccines is considered as a promising strategy. Here, we introduce adeno-associated virus (AAV) vectors, widely used for

Indexed as

AAV capsid engineeringcancer immunotherapyprime-boostsingle administrationvaccine

Identifiers

PMID37090479
PMCPMC10120303
OpenAlexW4328097607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.