Evidence map›Paper›PMID 37089690›Full record

ArticleFrontiers in molecular neuroscience2023

GLP-1 enhances hyperpolarization-activated currents of mouse cerebellar Purkinje cell

Yang Liu, Li-Xin Cao, Wei-Yao Wang, Yong-Rui Piao, Jun-Ya Wang, Chun-Ping Chu, Yan-Hua Bing, De-Lai Qiu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yang LiuDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, Jilin, China.
Li-Xin CaoDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, Jilin, China.
Wei-Yao WangDepartment of Physiology, College of Basic Medicine, Jilin Medical University, Jilin, Jilin, China.
Yong-Rui PiaoDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, Jilin, China.
Jun-Ya WangDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, Jilin, China.
Chun-Ping ChuDepartment of Physiology, College of Basic Medicine, Jilin Medical University, Jilin, Jilin, China.
Yan-Hua BingFunctional Experiment Center, College of Medicine, Yanbian University, Yanji, Jilin, China.
De-Lai QiuDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, Jilin, China.
Yanbian University · CNJilin Medical University · CNYanbian University Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucagon-like peptide-1 (GLP-1) is mainly secreted by preglucagonergic neurons in the nucleus tractus solitarius, which plays critical roles in regulation of neuronal activity in the central nervous system through its receptor. In the cerebellar cortex, GLP-1 receptor is abundantly expressed in the molecular layer, Purkinje cell (PC) layer and granular layer, indicating that GLP-1 may modulate the cerebellar neuronal activity. In this study, we investigated the mechanism by which GLP1 modulates mouse cerebellar PC activity

Indexed as

cerebellar Purkinje cellglucagon-like peptide-1 (GLP-1)hyperpolarization-activated current (IH)protein kinase Awhole-cell patch-clamp recording

Identifiers

PMID37089690
PMCPMC10113493
OpenAlexW4362626435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.