Evidence map›Paper›PMID 37089325›Full record

ReviewHeliyon2023

Oxygen therapy alternatives in COVID-19: From classical to nanomedicine.

Luis F T Pereira, Camila A Dallagnol, Tassiana H Moulepes, Clara Y Hirota, Pedro Kutsmi, Lucas V Dos Santos, Cleverton L Pirich, Guilherme F Picheth

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. COVID-19 in Children: Molecular Profile and Pathological Features.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luis F T PereiraSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Camila A DallagnolSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Tassiana H MoulepesSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Clara Y HirotaSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Pedro KutsmiSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Lucas V Dos SantosDepartment of Biochemistry, Federal University of Paraná, Curitiba, PR, Brazil.
Cleverton L PirichDepartment of Bioprocess Engineering and Biotechnology, Federal University of Paraná, Curitiba, PR, Brazil.
Guilherme F PichethSchool of Medicine, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Pontifícia Universidade Católica do Paraná · BRUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Around 10-15% of COVID-19 patients affected by the Delta and the Omicron variants exhibit acute respiratory insufficiency and require intensive care unit admission to receive advanced respiratory support. However, the current ventilation methods display several limitations, including lung injury, dysphagia, respiratory muscle atrophy, and hemorrhage. Furthermore, most of the ventilatory techniques currently offered require highly trained professionals and oxygen cylinders, which may attain short supply owing to the high demand and misuse. Therefore, the search for new alternatives for oxygen therapeutics has become extremely important for maintaining gas exchange in patients affected by COVID-19. This review highlights and suggest new alternatives based on micro and nanostructures capable of supplying oxygen and/or enabling hematosis during moderate or acute COVID-19 cases.

Indexed as

COVID-19HypoxiaMicrobubblesNanobubblesNanotechnologyOxygen therapy

Identifiers

PMID37089325
PMCPMC10106793
OpenAlexW4366124614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.