Evidence map›Paper›PMID 37088297›Full record

ArticleClinical immunology (Orlando, Fla.)2023

Blocking activation of CD4

Eula Graciele Amorim Neves, Carolina Cattoni Koh, Pedro Paulo Diniz Lucinda, Thaiany Goulart Souza-Silva, Nayara I Medeiros, Alexandre Pantaleão, Antônio Mutarelli, Juliana de Assis Silva Gomes, Silvana de Araújo Silva, Kenneth John Gollob and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical immunology (Orlando, Fla.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Eula Graciele Amorim NevesLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Carolina Cattoni KohLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Pedro Paulo Diniz LucindaLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Thaiany Goulart Souza-SilvaLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Nayara I MedeirosLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Alexandre PantaleãoDepto. Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - Santa Efigênia, Belo Horizonte, MG 30130-100, Brazil.
Antônio MutarelliDepto. Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - Santa Efigênia, Belo Horizonte, MG 30130-100, Brazil.
Juliana de Assis Silva GomesLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil.
Silvana de Araújo SilvaDepto. Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - Santa Efigênia, Belo Horizonte, MG 30130-100, Brazil.
Kenneth John GollobHospital Israelita Albert Einstein, Av. Albert Einstein, 627/701 - Morumbi, São Paulo, SP 05652-900, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, INCT-DT, Salvador, BA, Brazil.
Maria do Carmo Pereira NunesDepto. Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - Santa Efigênia, Belo Horizonte, MG 30130-100, Brazil.
Walderez Ornelas DutraLab. Biologia das Interações Celulares, Depto. Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627 - Pampulha, Belo Horizonte, MG 31270-901, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, INCT-DT, Salvador, BA, Brazil. Electronic address: waldutra@gmail.com.
Universidade Federal de Minas Gerais · BRHospital Israelita Albert Einstein · BR

Funding

Role of CD4-CD8- DN T cells in Chagas CardiomyopathyR01AI138230 · NIAID · FOUNDATION FOR RESEARCH DEVELOPMENT · PI DUTRA, WALDEREZ O. · 2018 to 2021
$540k
NIAID NIH HHS R01 AI138230
6 · The paper itself

Abstract

CD4

Indexed as

Antineoplastic AgentsChagas CardiomyopathyChagas DiseaseTrypanosoma cruziCD8-Positive T-LymphocytesCytokinesHumansAntineoplastic AgentsCytokinesCardiomyopathyChagas diseaseChemokine receptorsCytotoxic moleculesDN T cellsInflammation

Identifiers

PMID37088297
PMCPMC10257888
OpenAlexW4366779586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.