Evidence map›Paper›PMID 37088278›Full record

ArticleThe Journal of investigative dermatology2023

Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4.

Ravi W Sun, Haihong Zhang, Syed J Mehdi, Gresham T Richter, Hayden H Bowman, Jessica Sifford, Chelsea Smith, Alexander K Burnett, Alexander Layman, Charity L Washam and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ravi W SunArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Haihong ZhangArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Syed J MehdiArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Gresham T RichterArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Hayden H BowmanArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Jessica SiffordArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Chelsea SmithArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Alexander K BurnettArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Alexander LaymanArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Charity L WashamArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
Stephanie D ByrumArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA.
James T BennettCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington, USA.
Dana M JensenCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington, USA.
Victoria DmyterkoCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington, USA.
Jonathan A PerkinsDivision of Pediatric Otolaryngology-Seattle Children's Hospital, Seattle, Washington, USA.
Carrie J ShawberDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, New York, USA; Department of Surgery, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
June K WuDepartment of Surgery, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Graham M StrubArkansas Children's Research Institute (ACRI), Little Rock, Arkansas, USA; Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. Electronic address: gstrub@uams.edu.

Funding

Translational Regulation in Normal Erythropoiesis and Diamond Blackfan AnemiaP20GM121293 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI Alan Tackett · 2017 to 2026
$27.6M
Mosaic: post-zygotic mutations in vascular malformationsR01HL130996 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI BENNETT, JAMES T · 2016 to 2024
$7.5M
Systems Pharmacology and Toxicology Training ProgramT32GM106999 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI PRATHER, PAUL L · 2013 to 2022
$1.4M
Altered miRNA Expression Drives Proliferation of Lymphatic Malformation by Activating Pro-Growth Signaling CascadesF30HL165803 · NHLBI · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI SUN, RAVI · 2023 to 2025
$132k
NHLBI NIH HHS F30 HL165803NHLBI NIH HHS R01 HL130996NIGMS NIH HHS P20 GM121293NIGMS NIH HHS T32 GM106999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endothelial CellsMicroRNAsApoptosis Regulatory ProteinsCell ProliferationApoptosis Regulatory ProteinsMicroRNAs

Identifiers

PMID37088278
PMCPMC10524134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.