ArticleOsteoarthritis and cartilage2023
Prevalence of intra-articular mineralization on knee computed tomography: the multicenter osteoarthritis study.
Article in Osteoarthritis and cartilage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- The association between articular calcium crystal deposition and knee osteoarthritis, joint pain and inflammation: a cross-sectional study.Skeletal radiology · 2025Trial
- The association of CT-detected intra-articular calcification with MRI-detected effusion-synovitis and Hoffa-synovitis in knee OA: The Multicenter Osteoarthritis study.Osteoarthritis and cartilage · 2026Observational
- Review
- A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture.Journal of visualized experiments : JoVE · 2026Article
- Imaging and management of calcium pyrophosphate deposition disease.Skeletal radiology · 2025Review
- Measures of Patellofemoral Morphology Predict the Risk of Local Cartilage Damage Progression: A Yale/MOST Collaborative Study.The American journal of sports medicine · 2025Article
- Study on the Predictive Value of Inflammatory Factors and Biomarkers in Synovial Fluid for Disease Progression in Knee Osteoarthritis Patients.Journal of musculoskeletal & neuronal interactions · 2025Article
- Semiautomated Three-Dimensional Landmark Placement on Knee Models Is a Reliable Method to Describe Bone Shape and Alignment.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Intra-Articular Mineralization on Computerized Tomography of the Knee and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study.Arthritis & rheumatology (Hoboken, N.J.) · 2024Article
- Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study.Arthritis & rheumatology (Hoboken, N.J.) · 2023Article
- Radiographically detectable intra-articular mineralization: Predictor of knee osteoarthritis outcomes or only an indicator of aging? A brief report from the osteoarthritis initiative.Osteoarthritis and cartilage open · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
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Abstract
objectiveThe aim of this work was to report the prevalence of computed tomography (CT)-detected intra-articular mineralization.
designWe included participants from the Multicenter Osteoarthritis (MOST) Study. At the 12th year visit of the MOST study, bilateral knee CTs were first obtained. All participants also had posteroanterior and lateral radiographs of bilateral knees and completed standard questionnaires. Knee radiographs were assessed for Kellgren & Lawrence grade (KLG) and radiographic evidence of intra-articular mineralization. CT images were scored using the Boston University Calcium Knee Score (BUCKS) for cartilage, menisci, ligaments, capsule, and vasculature. Prevalence of intra-articular mineralization was computed for the total sample, and stratified by age, sex, race, Body Mass Index (BMI), presence of frequent knee pain, and KLG. We also determined distribution of mineralization in the cartilage and meniscus, and co-localization.
results4140 bilateral knees from 2070 participants were included (56.7% female, mean age 61.1 years, mean BMI: 28.8 kg/m
conclusionsCT of the knee provides greater visualization of intra-articular mineralization than radiographs and allows better localization of the crystal deposition within the joint. Further studies should focus on the co-localization of intra-articular crystal deposition and corresponding magnetic resonance imaging (MRI)-features of knee osteoarthritis (OA).
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