Evidence map›Paper›PMID 37088104›Full record

Observational studyJournal of the American Medical Directors Association2023

Potentially Harmful Medication Prescribing by the Degree of Physician Specialization in Nursing Home Practice: An Observational Study.

Kira Ryskina, Derrick Lo, Tingting Zhang, Lauren Gerlach, Julie Bynum, Theresa I Shireman

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Medical Directors Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Impact of national partnership to improve dementia care on antipsychotic use duration for dementia residents in nursing homes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kira RyskinaLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: ryskina@pennmedicine.upenn.edu.
Derrick LoCenter for Gerontology & Healthcare Research, Brown University School of Public Health, Providence, RI, USA.
Tingting ZhangCenter for Gerontology & Healthcare Research, Brown University School of Public Health, Providence, RI, USA.
Lauren GerlachInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.
Julie BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Theresa I ShiremanCenter for Gerontology & Healthcare Research, Brown University School of Public Health, Providence, RI, USA.
Brown University · USUniversity of Michigan · USUniversity of Pennsylvania · US

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Post-acute Care Outcomes of Patients with Alzheimer's Disease and Related Dementias: the Role of Skilled Nursing Facility SpecialistsR01AG070944 · NIA · UNIVERSITY OF PENNSYLVANIA · PI JUNG, HYE-YOUNG, RYSKINA, KIRA L · 2021 to 2025
$3.2M
Post-acute care of older adults: the role of skilled nursing facility specialistsR01AG066841 · NIA · UNIVERSITY OF PENNSYLVANIA · PI RYSKINA, KIRA L · 2020 to 2024
$2.0M
UNDERSTANDING THE ROLE OF PHYSICIAN INTEGRATION WITHIN NURSING HOMES IN POST-ACUTE CARE OUTCOMESK08AG052572 · NIA · UNIVERSITY OF PENNSYLVANIA · PI RYSKINA, KIRA L · 2016 to 2020
$821k
NIA NIH HHS K08 AG052572NIA NIH HHS L30 AG057071NIA NIH HHS P01 AG027296NIA NIH HHS R01 AG066841NIA NIH HHS R01 AG070944
6 · The paper itself

Abstract

objectivesThe use of anticholinergics, antipsychotics, benzodiazepines, and other potentially harmful medications (PHMs) is associated with particularly poor outcomes in nursing home (NH) residents with Alzheimer's disease and related dementias (ADRD). Our objective was to compare PHM prescribing by NH physicians and advanced practitioners who focus their practice on NH residents (NH specialists) vs non-NH specialists.

designRetrospective cohort study. SETTING AND

participantsWe included a 20% random sample of Medicare beneficiaries with ADRD who resided in 12,278 US NHs in 2017. Long-stay NH residents with ADRD were identified using MDS, Medicare Parts A and B claims. Residents <65 years old or without continuous Part D coverage were excluded.

methodsPhysicians in generalist specialties and advanced practitioners with ≥90% of Part B claims for NH care were considered NH specialists. Residents were assigned to NH specialists vs non-NH specialists based on plurality of Part D claims submitted for that resident. Any PHM use (defined using the Beers Criteria) and the proportion of NH days on a PHM were modeled using generalized estimating equations. Models included resident demographics, clinical characteristics, cognitive and functional status, behavioral assessments, and facility characteristics.

resultsOf the 54,713 residents in the sample, 27.9% were managed by an NH specialist and 72.1% by a non-NH specialist. There was no statistically significant difference in any PHM use [odds ratio (OR) 0.97, 95% CI 0.93-1.02, P = .23]. There were lower odds of prolonged PHM use (OR 0.87, 95% CI 0.81-0.94, P < .001, for PHM use on >75% vs >0%-<25% of NH days) for NH specialists vs non-NH specialists. CONCLUSIONS AND IMPLICATIONS: Although the use of PHMs among NH residents with ADRD managed by NH specialists was not lower, they were less likely to receive PHMs over longer periods of time. Future work should evaluate the underlying causes of these differences to inform interventions to improve prescribing for NH residents.

Indexed as

MedicarePhysiciansAgedHumansNursing HomesRetrospective StudiesSkilled Nursing FacilitiesUnited Statesantipsychoticsnursing homephysiciansPotentially harmful medicationsspecialization

Identifiers

PMID37088104
PMCPMC10524654
OpenAlexW4366524822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.