Evidence map›Paper›PMID 37087752›Full record

ArticleIslets2023

Quality of life after total pancreatectomy with islet autotransplantation for chronic pancreatitis in Japan.

Tadashi Takaki, Daisuke Chujo, Toshiaki Kurokawa, Akitsu Kawabe, Nobuyuki Takahashi, Kyoji Ito, Koji Maruyama, Fuyuki Inagaki, Koya Shinohara, Kumiko Ajima and 11 more

Open access · goldAbstract read
In one paragraph

Article in Islets, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Tadashi TakakiDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Daisuke ChujoDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Toshiaki KurokawaDepartment of Surgery, JCHO Tokyo Takanawa Hospital, Tokyo, Japan.
Akitsu KawabeDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Nobuyuki TakahashiDepartment of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.
Kyoji ItoHepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Koji MaruyamaDepartment of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.
Fuyuki InagakiHepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Koya ShinoharaDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Kumiko AjimaDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Yzumi YamashitaDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Hiroshi KajioDepartment of Diabetes, Endocrinology and Metabolism, National Center for Global health and Medicine, Tokyo, Japan.
Mikio YanaseDepartment of Gastroenterology, National Center for Global Health and Medicine, Tokyo, Japan.
Chihaya HinoharaPalliative care, National Center for Global Health and Medicine, Tokyo, Japan.
Makoto TokuharaPalliative care, National Center for Global Health and Medicine, Tokyo, Japan.
Yukari UemuraCenter for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Yoshihiro EdamotoDepartment of Surgery, Secomedic Hospital, Chiba, Japan.
Nobuyuki TakemuraHepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Norihiro KokudoHepato-Biliary-Pancreatic Surgery Division, Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Shinichi MatsumotoDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
Masayuki ShimodaDepartment of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, Tokyo, Japan.
National Center for Global Health and Medicine · JPChiba Hospital · JPKyoto University · JPToyama University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with chronic pancreatitis (CP) often have severe and intractable abdominal pain, leading to decreased quality of life (QOL), inability to work or attend school, and increased health care costs due to repeated emergency room visits and hospitalizations.

methodsWe evaluated the efficacy of total pancreatectomy and islet autotransplantation (TPIAT) in terms of pain control and QOL in CP patients treated at our center in Japan. To evaluate QOL, we used the Short-Form 36 Health Survey version 2 (SF-36v2

resultsBetween August 2016 and June 2019, we performed this procedure in 5 patients. All patients were followed up for 12 months and all transplanted islets were still functioning at the 1-year follow-up. The major adverse events were abdominal wall hemorrhage, intestinal obstruction, intra-abdominal abscess, and abdominal pain requiring hospitalization; no case had sequelae. No major complications were due to islet transplantation. Pain scores improved postoperatively in all patients. Three QOL item dimensions role-physical (

conclusionThe QOL improvement after TPIAT for CP suggests its effectiveness in the Japanese population.

Indexed as

Islets of Langerhans TransplantationPancreatitis, ChronicAbdominal PainHumansJapanPancreatectomyQuality of LifeTransplantation, AutologousTreatment OutcomeAutologous transplantationchronic pancreatitis: abdominal painglycemic controlislet transplantationpancreatectomyquality of life (QOL)

Identifiers

PMID37087752
PMCPMC10124982
OpenAlexW4366777503

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.