Evidence map›Paper›PMID 37087421›Full record

ArticleBMC nephrology2023

SGLT-2 inhibitors may increase ultrafiltration in incident peritoneal dialysis patients: a case report.

Jia-Wen Lai, Hsuan-Jen Lin, Che-Yi Chou

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jia-Wen LaiDivision of Nephrology, Asia University Hospital, Wufeng, Taichung, Taiwan.
Hsuan-Jen LinDivision of Nephrology, Asia University Hospital, Wufeng, Taichung, Taiwan.
Che-Yi ChouDivision of Nephrology, Asia University Hospital, Wufeng, Taichung, Taiwan. cychou.chou@gmail.com.ORCID 0000-0003-4029-9097
Asia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdequate fluid removal to achieve euvolemic status can be difficult in patients with incident peritoneal dialysis (PD). Limited treatments such as increased high dextrose PD solutions and icodextrin are currently available. We reported four incident PD patients whose' ultrafiltration volume was increased after sodium-glucose cotransporter-2 inhibitors. CASE PRESENTATION: The four reported cases were diabetic kidney disease stage 5 (cases 1-3) and IgA nephritis (case 4) patients whostartedt PD because of acute pulmonary edema (case 1 and 3), nausea vomiting (case 2), and hyperkalemia (case 4). They had an ultrafiltration volume of 700-1000 ml per day but hpersistentted peripheral pitting edema or pulmonary edema. Their ultrafiltration volincreased after dapagliflozin 5 mg daily, and the fluid overload symptoms ere improved. No hypotension, or hypoglycemia was found, and the urine was not increased during dapagliflozin treatment.

conclusionsSGLT-2 inhibitors may increase ultrafiltration in incident PD patients. More studies are needed to support the safety of SGLT-2 inhibitors in PD patients.

Indexed as

Peritoneal DialysisPulmonary EdemaSodium-Glucose Transporter 2 InhibitorsBenzhydryl CompoundsDialysis SolutionsGlucoseGlucosidesHumansUltrafiltrationBenzhydryl CompoundsdapagliflozinDialysis SolutionsGlucoseGlucosidesSodium-Glucose Transporter 2 InhibitorsCase reportperitoneal dialysisSGLT-2 inhibitorsUltrafiltration

Identifiers

PMID37087421
PMCPMC10122385
OpenAlexW4366768438

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.