Evidence map›Paper›PMID 37087039›Full record

ArticleWorld neurosurgery2023

Establishment of Age- and Sex-Specific Reference Cerebral Ventricle Volumes.

Ryan T Kellogg, Min S Park, M Harrison Snyder, Alexandria Marino, Sohil Patel, Xue Feng, Jan Vargas

Open access · greenAbstract read
In one paragraph

Article in World neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ryan T KelloggDepartment of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA. Electronic address: rtk4u@virginia.edu.
Min S ParkDepartment of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.
M Harrison SnyderUniversity of Virginia School of Medicine, Charlottesville, Virginia, USA.
Alexandria MarinoDepartment of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.
Sohil PatelDepartment of Radiology, University of Virginia, Charlottesville, Virginia, USA.
Xue FengDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Jan VargasNeurosurgery, Prisma Health Upstate, Greenville, South Carolina, USA.
Neurological Surgery · USUniversity of Virginia · USPrisma Health · US

Funding

Improved Diagnosis of Shunt Malfunction with Automatic Quantification of Ventricular SpaceR41NS125874 · NINDS · CARINA MEDICAL, LLC · PI FENG, XUE · 2022 to 2022
$340k
NINDS NIH HHS R41 NS125874
6 · The paper itself

Abstract

backgroundThe diagnosis of hydrocephalus is dependent on clinical symptoms and radiographic findings including ventriculomegaly. Our goal was to generate a data set of ventricular volume utilizing non-pathologic computed tomography (CT) scans for adults to help define reference ventricle size.

methodsWe performed a retrospective analysis of non-contrast head CTs for adults at a single institution to identify patients who had undergone imaging and did not have a diagnosis of hydrocephalus, history of ventriculoperitoneal shunting, or treatments for hydrocephalus. A convolutional neural network was trained on hand-segmented scans from a variety of age ranges and then utilized to automate the segmentation of the entire data set.

resultsVentricles on 866 CT scans were segmented to generate a reference range of volumes for both male and female individuals ranging in age from 18-99 years. The generated data were binned by age ranges.

conclusionsWe have developed a convolutional neural network that can segment the ventricles on CT scans of adult patients over a range of ages. This network was used to measure the ventricular volume of non-pathologic head CTs to produce reference ranges for several age bins. This data set could be utilized to aid in the diagnosis of hydrocephalus by comparing potentially pathologic scans to reference ventricular volumes.

Indexed as

Cerebral VentriclesHydrocephalusAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedVentriculoperitoneal ShuntYoung AdultArtificial intelligenceDeep learningHydrocephalusSegmentationVentricleVentriculomegaly

Identifiers

PMID37087039
PMCPMC11729395
OpenAlexW4366607066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.