Evidence map›Paper›PMID 37086916›Full record

ArticleContemporary clinical trials2023

A multi-site trial of an electronic health integrated physical activity promotion intervention in breast and endometrial cancers survivors: MyActivity study protocol.

Lisa Cadmus-Bertram, Payton Solk, Megan Agnew, Julia Starikovsky, Christian Schmidt, Whitney A Morelli, Vanessa Hodgson, Hannah Freeman, Laura Muller, Abby Mishory and 12 more

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04262180 (Multi-site Adaptive Trial of a Technology-based, EHR-integrated Physical Activity Intervention in Breast and Endometrial Cancer Survivors), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04262180 nacompletednot on this map

Multi-site Adaptive Trial of a Technology-based, EHR-integrated Physical Activity Intervention in Breast and Endometrial Cancer Survivors

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2020 to 2025Enrolled323ConditionsPhysical Activity, Breast Cancer Survivors, Endometrial Cancer SurvivorsArmsBase intervention-Fitbit with EHR integration, Coaching Calls, Online Gym
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 2 countries.

Lisa Cadmus-BertramThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Payton SolkNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Megan AgnewThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Julia StarikovskyNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Christian SchmidtThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Whitney A MorelliMedical College of Wisconsin, Department of Physical Medicine and Rehabilitation, Milwaukee, WI, United States of America.
Vanessa HodgsonThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Hannah FreemanNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Laura MullerThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Abby MishoryNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Sondra NaxiThe University of Wisconsin-Madison, Department of Kinesiology, Madison, WI, United States of America.
Lillian CardenNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Amye J TevaarwerkMayo Clinic Comprehensive Cancer Center, Rochester, MN, United States of America.
Melanie WolterNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Emma BarberNorthwestern University Feinberg School of Medicine, Department of Obstetrics and Gynecology, Chicago, IL, United States of America.
Ryan SpencerThe University of Wisconsin-Madison, Department of Obstetrics and Gynecology, Madison, WI, United States of America.
Mary E SestoThe University of Wisconsin-Madison, Department of Medicine, Madison, WI, United States of America.
William GradisharNorthwestern University Feinberg School of Medicine, Department of Medicine, Chicago, IL, United States of America.
Ronald GangnonThe University of Wisconsin-Madison, Department of Population Health Sciences and Department of Biostatistics & Medical Informatics, Madison, WI, United States of America.
Bonnie SpringNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America.
Inbal Nahum-ShaniUniversity of Michigan, Institute for Social Research, Ann Arbor, MI, United States of America.
Siobhan M PhillipsNorthwestern University Feinberg School of Medicine, Department of Preventive Medicine, Chicago, IL, United States of America. Electronic address: smphillips@northwestern.edu.
Northwestern University · USUniversity of Wisconsin–Madison · USInstitute for Social Research · NOMayo Clinic in Florida · USMedical College of Wisconsin · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Inbal Billie Nahum-Shani · 2021 to 2026
$18.2M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
Multi-site adaptive trial of a technology-based, EHR-integrated physical activity intervention in breast and endometrial cancer survivorsR37CA225877 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PHILLIPS, SIOBHAN MARIE · 2019 to 2025
$4.8M
Designing with Dissemination in Mind: Optimization of a mHealth Physical Activity Intervention for Breast Cancer SurvivorsK07CA196840 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PHILLIPS, SIOBHAN MARIE · 2015 to 2019
$729k
Sedentary Behavior and Breast Cancer: Interventions and BiomarkersK07CA178870 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CADMUSBERTRAM, LISA ANNE · 2014 to 2017
$547k
NCATS NIH HHS UL1 TR002373NCI NIH HHS K07 CA178870NCI NIH HHS K07 CA196840NCI NIH HHS R37 CA225877NIDA NIH HHS P50 DA054039NIDA NIH HHS R01 DA039901
6 · The paper itself

Abstract

Despite the known benefits of moderate-to-vigorous physical activity (MVPA) for breast and endometrial cancer survivors, most are insufficiently active, interventions response is heterogeneous, and MVPA programming integration into cancer care is limited. A stepped care approach, in which the least resource-intensive intervention is delivered first and additional components are added based on individual response, is one strategy to enhance uptake of physical activity programming. However, the most effective intervention augmentation strategies are unknown. In this singly randomized trial of post-treatment, inactive breast and endometrial cancer survivors (n = 323), participants receive a minimal intervention including a Fitbit linked with their clinic's patient portal and, in turn, the electronic health record (EHR) with weekly feedback delivered via the portal. MVPA progress summaries are sent to participants' oncology team via the EHR. MVPA adherence is evaluated at 4, 8, 12, 16 and 20 weeks; non-responders (those meeting ≤80% of the MVPA goal over previous 4 weeks) at each timepoint are randomized once for the remainder of the 24-week intervention to one of two "step-up" conditions: (1) online gym or (2) coaching calls, while responders continue with the minimal Fitbit+EHR intervention. The primary outcome is ActiGraph-measured MVPA at 24 and 48 weeks. Secondary outcomes include symptom burden and functional performance at 24 and 48 weeks. This trial will inform development of an effective, scalable, and tailored intervention for survivors by identifying non-responders and providing them with the intervention augmentations necessary to increase MVPA and improve health outcomes. Clinical Trials Registration # NCT04262180.

Indexed as

Cancer SurvivorsEndometrial NeoplasmsExerciseFemaleFitness TrackersHealth PromotionHumansMulticenter Studies as TopicRandomized Controlled Trials as TopicSurvivorsAdaptive interventionBreast cancercancer survivorshipDigital healthEndometrial cancerPhysical activity

Identifiers

PMID37086916
PMCPMC10413251
OpenAlexW4366606924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.