ReviewCell biochemistry and biophysics2023
Citrus Essential Oils: A Rational View on its Chemical Profiles, Mode of Action of Anticancer Effects/Antiproliferative Activity on Various Human Cancer Cell Lines.
Review in Cell biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 18 citations in OpenAlex.
- Determination of optimum extract conditions and evaluation of biological activity potential of Salvia cilicica Boiss.Scientific reports · 2025Article
- Article
- Alginate Nanoparticles ContainingInternational journal of biomaterials · 2024Article
- Gut-Microbiome Interactions: Characterization, Therapeutic Implications and Machine Learning.Sage open pathologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a complex genetic disorder due to uncontrolled growth of abnormal cells in the body, causes damage to the immune system, and may lead to life-threatening situations. Common approaches to cancer treatment includes chemotherapy, hormone therapy, immunotherapy, radiation therapy etc. Development of novel and natural chemotherapeutic agents is highly demanded because of the side effects of synthetic drugs. Essential oils from aromatic plants exhibited antioxidant, antimutagenic, antiproliferative and immunomodulating activities. Mechanism of multidrug resistance and synergistic action of these volatile constituents are responsible for their chemopreventive properties. These oils primarily comprising of terpenoid constituents and are characterized by volatility, aroma, low molecular weight etc. The chemical composition of these oils varies depending on the environmental condition, species, plant part and geographical region. Literature analysis revealed that plant essential oils play an important role in cancer prevention and treatment. Cancer patients exposed to essential oils via inhaler devices were found to have less anxiety, stress, and nausea and insomnia. Nowadays, there is an increasing demand for investigating the biological properties of aromatic plants due to their availability, chemical diversity, and low toxicity. In aromatherapy, Citrus essential oils repress cancer related pain and enhance immune system. Current review summarizes existing variability of the chemical composition of Citrus essential oils and its molecular level anticancer mechanism against various human cancer cell lines. Citrus essential oils enhance cytotoxicity, antiproliferative and apoptotic behavior of cancer cell lines. Since essential oils exhibiting significant anticancer potential is worthy of further investigation for cancer chemoprevention. The findings of various research activities can be exploited by cancer researchers world wide for the development of anticancer drugs which can relieve cancer symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.