ReviewNeuromolecular medicine2023
Pathophysiological Links Between Obesity and Dementia.
Review in Neuromolecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Independent and Combined Effects of Obesity and Cardiovascular Diseases on the Risk of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of Prospective Cohort Studies Involving 8,276,914 Participants.International journal of molecular sciences · 2026Pooled it
- Association between unhealthy lifestyles and young-onset dementia: a nationwide cohort study.European archives of psychiatry and clinical neuroscience · 2026Article
- The association between cognitive function trajectories and all-cause mortality in middle-aged and older Chinese adults with cardiovascular disease: A longitudinal study from CHARLS.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- The alteration of brain function in overweight/obese individuals and the neurological benefit of thymoquinone: uncovering molecular mechanisms.Metabolic brain disease · 2026Review
- Surgical removal of visceral adipose tissue has therapeutic benefit in male APPFrontiers in endocrinology · 2026Article
- Neuroprotective effects ofFrontiers in nutrition · 2026Article
- Obesity-associated gut microbiome influences diet-induced metabolic and cognitive outcomes in older adults.Gut microbes reports · 2026Article
- Prevalence of neurocognitive dysfunction and associated risk factors among follow-up diabetic type 2 patients in diabetes center of Al-Thawra hospital, SanaFrontiers in endocrinology · 2026Article
- Capsaicin camphor and caffeic acid reduce adipogenesis and promote lipolysis with TRPV1 involvement.Scientific reports · 2025Article
- Association of Android and Gynoid Fatness With Incident Dementia and Brain Structure.Journal of cachexia, sarcopenia and muscle · 2025Article
- Sex-specific association between body roundness index and cognitive impairment among hospitalized middle-aged and elderly patients with type 2 diabetes in China: a cross-sectional analysis.European journal of medical research · 2025Article
- Protecting vascular health: the role of flavonoids during pregnancy complications in mitigating the risk of vascular dementia later in life.Inflammopharmacology · 2025Review
- Altered cognitive function in obese patients: relationship to gut flora.Molecular and cellular biochemistry · 2025Review
- Impact of sleep apnea on alzheimer's disease in relation to sex: an 8-year longitudinal follow-up study of a nationwide cohort.Alzheimer's research & therapy · 2025Article
- Article
- Nutritional strategies against dementia in rural populations.Frontiers in nutrition · 2025Review
- Soymilk yogurt prepared usingCurrent research in food science · 2025Article
- Association between changes in obesity status and neuropsychiatric health and brain structure in different glucose status.Frontiers in nutrition · 2025Article
- Could the Early Detection of Atrial Fibrillation Reduce the Risk of Developing Dementia?Biomedicines · 2024Review
- Body roundness index and cognitive function in older adults: a nationwide perspective.Frontiers in aging neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a major global health concern, with prevalence rates rapidly rising due to increased availability of highly processed foods rich in fats and/or sugars and technological advances promoting more sedentary behaviour. There is increasing evidence to suggest that obesity predisposes individuals to developing cognitive impairment and dementia. However, the relationship between the brain and the peripheral metabolic state is complex, and many of the underlying mechanisms of cognitive impairment in obesity are yet to be fully elucidated. To better understand the links between obesity and dementia, further work is required to determine pathological changes occurring in the brain during obesity. In this mini-review, we discuss the role of two pathological features of obesity (the gut-brain axis and systemic inflammation) and their potential contribution to dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.