Evidence map›Paper›PMID 37086367›Full record

ArticleGeroScience2023

Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis.

Venkateswara R Gogulamudi, Jessica R Durrant, Adelola O Adeyemo, Huynh Mi Ho, Ashley E Walker, Lisa A Lesniewski

Open access · hybridFull text read
In one paragraph

Article in GeroScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Novel Insights into the Molecular Mechanisms of Atherosclerosis.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Venkateswara R GogulamudiInternal Medicine-Geriatrics, University of Utah, Salt Lake City, UT, USA.
Jessica R DurrantDallas Tissue Research, Dallas, TX, USA.
Adelola O AdeyemoInternal Medicine-Geriatrics, University of Utah, Salt Lake City, UT, USA.
Huynh Mi HoInternal Medicine-Geriatrics, University of Utah, Salt Lake City, UT, USA.
Ashley E WalkerDepartment of Human Physiology, University of Oregon, Eugene, OR, USA.
Lisa A LesniewskiInternal Medicine-Geriatrics, University of Utah, Salt Lake City, UT, USA. Lisa.Lesniewski@utah.edu.ORCID 0000-0002-2138-1450
University of Utah · USResearch Institute of Dallas · USUniversity of Oregon · US

Funding

Tissue senescence and age-associated metabolic dysfunction: the role of immune cell mediated inflammationR01AG076748 · NIA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Lisa A Lesniewski · 2023 to 2026
$1.8M
Mechanisms of augmented atherosclerotic progression with agingR01AG048366 · NIA · UNIVERSITY OF UTAH · PI LESNIEWSKI, LISA A · 2016 to 2020
$1.7M
Role of ARF6 in atherosclerotic burden and severityI01BX004492 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI LESNIEWSKI, LISA A · 2020 to 2023
–
BLRD VA I01 BX004492NIA NIH HHS R01 AG048366NIA NIH HHS R01 AG076748NIH HHS R01 AG048366
6 · The paper itself

Abstract

Using multiple mouse models, we explored the impact of aging on the size and severity of atherosclerotic lesions. In young, middle-aged and old apolipoprotein E knockout mice (ApoE

Indexed as

AtherosclerosisPlaque, AtheroscleroticAnimalsApolipoproteins EMiceMice, Inbred C57BLMice, KnockoutProprotein Convertase 9Apolipoproteins EPCSK9 protein, humanProprotein Convertase 9AgingAnimal models of human diseaseApoEAtherosclerosisPathophysiologyPcsk9Vascular biology

Identifiers

PMID37086367
PMCPMC10400524
OpenAlexW4366742659

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.