Evidence map›Paper›PMID 37086362›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer.

Gráinne Sheill, Lauren Brady, Brian Hayes, Anne-Marie Baird, Emer Guinan, Rishabh Vishwakarma, Caroline Brophy, Tatjana Vlajnic, Orla Casey, Verena Murphy and 18 more

3 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02453139 nacompletednot on this map

Evasion of Immune Editing by Circulating Tumour Cells in an Exercise Modifiable Mechanism Underlying Aggressive Behaviour in Obese Men With Prostate Cancer

TypeinterventionalSponsorUniversity of Dublin, Trinity CollegeRan2014 to 2017Enrolled67ConditionsProstate Cancer, ObesityArmsExercise
NCT07032584 narecruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Multimodal Telerehabilitation on Reducing Disparities in Rural Survivors of Metastatic Prostate Cancer

TypeinterventionalSponsorUniversity of UtahRan2025 to 2029Enrolled74ConditionsProstate Cancer, Metastatic Prostate Cancer, Androgen Deprivation TherapyArmsTelerehabilitation Intervention
NCT07093177 narecruitingnot on this mapstarted 2026, after this paper: background citation

Multimodal Telerehabilitation of Rural Patients With Advanced Prostate Cancer

TypeinterventionalSponsorUniversity of UtahRan2026 to 2028Enrolled30ConditionsProstate CancerArmsTelerehabilitation Unit
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 13 institutions in 4 countries.

Gráinne SheillDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland. sheillg@tcd.ie.
Lauren BradyDepartment of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Brian HayesDepartment of Histopathology, Cork University Hospital, Cork, Ireland.
Anne-Marie BairdDepartment of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Emer GuinanSchool of Medicine, Trinity College Dublin, Dublin, Ireland.
Rishabh VishwakarmaSchool of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland.
Caroline BrophySchool of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland.
Tatjana VlajnicInstitute of Pathology, University Hospital Basel, Basel, Switzerland.
Orla CaseyCancer Trials Ireland, Dublin, Ireland.
Verena MurphyCancer Trials Ireland, Dublin, Ireland.
John GreeneDepartment of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Emma AllottCentre for Cancer Research and Cell Biology, Queen's University Belfast, Northern Ireland, Belfast, UK.
Juliette HusseyDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland.
Fidelma CahillSchool of Cancer and Pharmaceutical Sciences, Translational Oncology and Urology Research (TOUR), King's College London, London, UK.
Mieke Van HemelrijckSchool of Cancer and Pharmaceutical Sciences, Translational Oncology and Urology Research (TOUR), King's College London, London, UK.
Nicola PeatGuy's and St Thomas' NHS Foundation Trust, London, UK.
Lorelei MucciHarvard T.H. Chan School of Public Health, Boston, MA, USA.
Moya CunninghamDepartment of Radiation Oncology, St Luke's Hospital, Dublin, Ireland.
Liam GroganDepartment of Oncology, Beaumont Hospital, Dublin, Ireland.
Thomas LynchDepartment of Urology, St James's Hospital, Dublin, Ireland.
Rustom P ManeckshaDepartment of Urology, St James's Hospital, Dublin, Ireland.
John McCaffreyDepartment of Oncology, Mater Misericordiae Hospital, Dublin, Ireland.
Dearbhaile O'DonnellHOPE Directorate, St James's Hospital, Dublin, Ireland.
Orla SheilsDepartment of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
John O'LearyDepartment of Histopathology, St James's Hospital, Dublin, Ireland.
Sarah RudmanGuy's and St Thomas' NHS Foundation Trust, London, UK.
Ray McDermottDepartment of Oncology, Tallaght University Hospital, Dublin, Ireland.
Stephen FinnDepartment of Histopathology and Morbid Anatomy, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Trinity College Dublin · IESt. James's Hospital · IECancer Trials Ireland · IEGuy's and St Thomas' NHS Foundation Trust · GBKing's College London · GBBeaumont Hospital · IECork University Hospital · IEHarvard University · USMater Misericordiae University Hospital · IESt. Luke's Hospital · IETallaght University Hospital · IEThe Northern Ireland Cancer Centre · GBUniversity Hospital of Basel · CH

Funding

Wellcome TrustWorld Cancer Research Fund 2013/1003
6 · The paper itself

Abstract

purposeAll patients living with cancer, including those with metastatic cancer, are encouraged to be physically active. This paper examines the secondary endpoints of an aerobic exercise intervention for men with metastatic prostate cancer.

methodsExPeCT (Exercise, Prostate Cancer and Circulating Tumour Cells), was a multi-centre randomised control trial with a 6-month aerobic exercise intervention arm or a standard care control arm. Exercise adherence data was collected via heart rate monitors. Quality of life (FACT-P) and physical activity (self-administered questionnaire) assessments were completed at baseline, at 3 months and at 6 months.

resultsA total of 61 patients were included (69.4 ± 7.3 yr, body mass index 29.2 ± 5.8 kg/m

conclusionIn a group of patients with a high burden of metastatic prostate cancer, a 6-month aerobic exercise intervention did not lead to change in quality of life. Further exercise studies examining the role of exercise for people living with metastatic prostate cancer are needed.

trial registrationThe trial was registered at clinicaltrials.gov (NCT02453139) on May 25th 2015.

Indexed as

Prostatic NeoplasmsQuality of LifeExerciseExercise TherapyHumansMaleSurveys and QuestionnairesAdvanced cancerExercisePhysical activityQuality of life

Identifiers

PMID37086362
PMCPMC10122616
OpenAlexW4366742302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.